Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | IKK16 | IKK | NFKB | 66.7 | uM | 7430.093 | 0.0065 | -0.8497 | 1.9432 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000171 | uM | 7431.1 | 1.0239 | 1.0305 | 1.5594 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000853 | uM | 7431.1 | 1.0000 | 1.0000 | 1.5594 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.00427 | uM | 7431.1 | 0.9720 | 0.9640 | 1.5594 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.0213 | uM | 7431.1 | 0.9987 | 0.9983 | 1.5594 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.107 | uM | 7431.1 | 1.0052 | 1.0066 | 1.5594 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.533 | uM | 7431.1 | 0.9119 | 0.8852 | 1.5594 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 2.67 | uM | 7431.1 | 0.8989 | 0.8679 | 1.5594 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 13.3 | uM | 7431.1 | 0.0633 | -0.6594 | 1.5594 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 66.7 | uM | 7431.1 | 0.0064 | -0.9220 | 1.5594 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000171 | uM | 10518.1 | 0.9658 | 0.9511 | 1.4056 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000853 | uM | 10518.1 | 0.9332 | 0.9040 | 1.4056 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.00427 | uM | 10518.1 | 0.9243 | 0.8911 | 1.4056 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.0213 | uM | 10518.1 | 0.9132 | 0.8749 | 1.4056 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.107 | uM | 10518.1 | 0.9356 | 0.9074 | 1.4056 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.533 | uM | 10518.1 | 0.9066 | 0.8652 | 1.4056 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 2.67 | uM | 10518.1 | 0.9114 | 0.8722 | 1.4056 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 13.3 | uM | 10518.1 | 0.0062 | -0.9465 | 1.4056 | |
| HCC1187 | TNBC | Basal A | IKK16 | IKK | NFKB | 66.7 | uM | 10518.1 | 0.0052 | -0.9524 | 1.4056 | |
| HCC1395 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000171 | uM | 7436.093 | 1.0288 | 1.0456 | 1.2596 | |
| HCC1395 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000853 | uM | 7436.093 | 1.0425 | 1.0672 | 1.2596 | |
| HCC1395 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.00427 | uM | 7436.093 | 1.0602 | 1.0950 | 1.2596 | |
| HCC1395 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.0213 | uM | 7436.093 | 1.0177 | 1.0281 | 1.2596 | |
| HCC1395 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.107 | uM | 7436.093 | 0.9889 | 0.9824 | 1.2596 | |
| HCC1395 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.533 | uM | 7436.093 | 0.8840 | 0.8136 | 1.2596 |