Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.00427 | uM | 7453.093 | 1.0565 | 1.0704 | 1.5872 | |
| HCC1937 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.0213 | uM | 7453.093 | 1.0717 | 1.0892 | 1.5872 | |
| HCC1937 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.107 | uM | 7453.093 | 1.0167 | 1.0210 | 1.5872 | |
| HCC1937 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.533 | uM | 7453.093 | 1.0703 | 1.0875 | 1.5872 | |
| HCC1937 | TNBC | Basal A | IKK16 | IKK | NFKB | 2.67 | uM | 7453.093 | 0.5842 | 0.4255 | 1.5872 | |
| HCC1937 | TNBC | Basal A | IKK16 | IKK | NFKB | 13.3 | uM | 7453.093 | 0.0137 | -0.8663 | 1.5872 | |
| HCC1937 | TNBC | Basal A | IKK16 | IKK | NFKB | 66.7 | uM | 7453.093 | 0.0076 | -0.9072 | 1.5872 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.000171 | uM | 7454.093 | 0.9201 | 0.8790 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.000853 | uM | 7454.093 | 0.7702 | 0.6446 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.00427 | uM | 7454.093 | 0.8545 | 0.7777 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.0213 | uM | 7454.093 | 0.9360 | 0.9032 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.107 | uM | 7454.093 | 0.9956 | 0.9934 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.533 | uM | 7454.093 | 0.8357 | 0.7483 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 2.67 | uM | 7454.093 | 0.5630 | 0.3004 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 13.3 | uM | 7454.093 | 0.0121 | -0.9269 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 66.7 | uM | 7454.093 | 0.0130 | -0.9228 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.000171 | uM | 7455.093 | 1.0750 | 1.0856 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.000853 | uM | 7455.093 | 1.0260 | 1.0300 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.00427 | uM | 7455.093 | 1.0340 | 1.0391 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.0213 | uM | 7455.093 | 1.0490 | 1.0562 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.107 | uM | 7455.093 | 1.0559 | 1.0641 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.533 | uM | 7455.093 | 0.9033 | 0.8856 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 2.67 | uM | 7455.093 | 0.3359 | 0.0627 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 13.3 | uM | 7455.093 | 0.0106 | -0.8567 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 66.7 | uM | 7455.093 | 0.0111 | -0.8527 | 1.7255 |