Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7898.001 | 0.4623 | 0.0700 | 1.2337 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7898.001 | 0.5216 | 0.1801 | 1.2337 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7898.001 | 0.3957 | -0.0566 | 1.2337 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7899.001 | 1.0300 | 1.0292 | 2.0444 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7899.001 | 0.9282 | 0.9284 | 2.0444 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7899.001 | 1.0461 | 1.0446 | 2.0444 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7899.001 | 0.7851 | 0.7768 | 2.0444 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7899.001 | 0.6747 | 0.6498 | 2.0444 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7899.001 | 0.4507 | 0.3543 | 2.0444 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7899.001 | 0.6057 | 0.5650 | 2.0444 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7899.001 | 0.6409 | 0.6088 | 2.0444 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7899.001 | 0.3331 | 0.1682 | 2.0444 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7900.001 | 0.9855 | 0.9636 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7900.001 | 0.7969 | 0.5028 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7900.001 | 0.9580 | 0.8948 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7900.001 | 0.8086 | 0.5305 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7900.001 | 0.7068 | 0.2921 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7900.001 | 0.5688 | -0.0169 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7900.001 | 0.6361 | 0.1316 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7900.001 | 0.5546 | -0.0477 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7900.001 | 0.4454 | -0.2775 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7902.001 | 1.1209 | 1.1214 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7902.001 | 0.7500 | 0.7238 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7902.001 | 1.0497 | 1.0507 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7902.001 | 0.7058 | 0.6706 | 1.9359 |