Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
Hs 578T	TNBC	Basal B	GSK923295	CENPE	Kinesin	33.3	uM	9511.001	0.0811	-0.7664	1.1698
LY2	HR+	Luminal	GSK923295	CENPE	Kinesin	0.0000853	uM	10264.001	1.0382	1.0495	1.5356
LY2	HR+	Luminal	GSK923295	CENPE	Kinesin	0.000427	uM	10264.001	1.0014	1.0018	1.5356
LY2	HR+	Luminal	GSK923295	CENPE	Kinesin	0.00213	uM	10264.001	1.0247	1.0321	1.5356
LY2	HR+	Luminal	GSK923295	CENPE	Kinesin	0.0107	uM	10264.001	0.9728	0.9644	1.5356
LY2	HR+	Luminal	GSK923295	CENPE	Kinesin	0.0533	uM	10264.001	0.7745	0.6934	1.5356
LY2	HR+	Luminal	GSK923295	CENPE	Kinesin	0.267	uM	10264.001	0.6449	0.5030	1.5356
LY2	HR+	Luminal	GSK923295	CENPE	Kinesin	1.33	uM	10264.001	0.7248	0.6219	1.5356
LY2	HR+	Luminal	GSK923295	CENPE	Kinesin	6.67	uM	10264.001	0.6969	0.5809	1.5356
LY2	HR+	Luminal	GSK923295	CENPE	Kinesin	33.3	uM	10264.001	0.3197	-0.0483	1.5356
MCF 10A	NM	Basal B	GSK923295	CENPE	Kinesin	0.0000853	uM	7870.001	1.0096	1.0093	2.0700
MCF 10A	NM	Basal B	GSK923295	CENPE	Kinesin	0.000427	uM	7870.001	0.9658	0.9666	2.0700
MCF 10A	NM	Basal B	GSK923295	CENPE	Kinesin	0.00213	uM	7870.001	0.9701	0.9709	2.0700
MCF 10A	NM	Basal B	GSK923295	CENPE	Kinesin	0.0107	uM	7870.001	0.9897	0.9900	2.0700
MCF 10A	NM	Basal B	GSK923295	CENPE	Kinesin	0.0533	uM	7870.001	0.6050	0.5689	2.0700
MCF 10A	NM	Basal B	GSK923295	CENPE	Kinesin	0.267	uM	7870.001	0.4358	0.3390	2.0700
MCF 10A	NM	Basal B	GSK923295	CENPE	Kinesin	1.33	uM	7870.001	0.4878	0.4139	2.0700
MCF 10A	NM	Basal B	GSK923295	CENPE	Kinesin	6.67	uM	7870.001	0.4537	0.3653	2.0700
MCF 10A	NM	Basal B	GSK923295	CENPE	Kinesin	33.3	uM	7870.001	0.1621	-0.1697	2.0700
MCF 10A	NM	Basal B	GSK923295	CENPE	Kinesin	0.0000853	uM	9551.001	1.0335	1.0247	2.6913
MCF 10A	NM	Basal B	GSK923295	CENPE	Kinesin	0.000427	uM	9551.001	0.9329	0.9491	2.6913
MCF 10A	NM	Basal B	GSK923295	CENPE	Kinesin	0.00213	uM	9551.001	1.0039	1.0029	2.6913
MCF 10A	NM	Basal B	GSK923295	CENPE	Kinesin	0.0107	uM	9551.001	1.0025	1.0019	2.6913
MCF 10A	NM	Basal B	GSK923295	CENPE	Kinesin	0.0533	uM	9551.001	0.4781	0.5204	2.6913
MCF 10A	NM	Basal B	GSK923295	CENPE	Kinesin	0.267	uM	9551.001	0.3101	0.2944	2.6913

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)