Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7863.001 | 1.0414 | 1.0468 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7863.001 | 0.9999 | 0.9999 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7863.001 | 1.0212 | 1.0241 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7863.001 | 0.4708 | 0.3017 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7863.001 | 0.3360 | 0.0740 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7863.001 | 0.2763 | -0.0393 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7863.001 | 0.3017 | 0.0100 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7863.001 | 0.2269 | -0.1415 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7864.001 | 0.9639 | 0.9515 | 1.4976 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7864.001 | 0.9243 | 0.8976 | 1.4976 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7864.001 | 1.0102 | 1.0136 | 1.4976 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7864.001 | 1.0509 | 1.0675 | 1.4976 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7864.001 | 0.4932 | 0.2475 | 1.4976 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7864.001 | 0.3263 | -0.0533 | 1.4976 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7864.001 | 0.2569 | -0.1929 | 1.4976 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7864.001 | 0.2944 | -0.1162 | 1.4976 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7864.001 | 0.1964 | -0.3254 | 1.4976 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 9511.001 | 1.0671 | 1.1143 | 1.1698 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 9511.001 | 0.9969 | 0.9947 | 1.1698 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 9511.001 | 1.0513 | 1.0874 | 1.1698 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 9511.001 | 0.9751 | 0.9574 | 1.1698 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 9511.001 | 0.5608 | 0.2199 | 1.1698 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.267 | uM | 9511.001 | 0.2991 | -0.2873 | 1.1698 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 1.33 | uM | 9511.001 | 0.2895 | -0.3068 | 1.1698 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 6.67 | uM | 9511.001 | 0.3198 | -0.2452 | 1.1698 |