Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HMT-3522 S1 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7911.001 | 0.9138 | 0.8553 | 1.2005 | |
| HMT-3522 S1 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7911.001 | 0.7626 | 0.5959 | 1.2005 | |
| HMT-3522 S1 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7911.001 | 0.7209 | 0.5228 | 1.2005 | |
| HMT-3522 S1 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7911.001 | 0.6813 | 0.4527 | 1.2005 | |
| HMT-3522 S1 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7911.001 | 0.1118 | -0.6776 | 1.2005 | |
| HMT-3522 S1 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7911.001 | 0.0119 | -0.9500 | 1.2005 | |
| HMT-3522 S1 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 10124.001 | 0.8914 | 0.8976 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 10124.001 | 0.8541 | 0.8608 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 10124.001 | 0.9498 | 0.9535 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 10124.001 | 0.9107 | 0.9163 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 10124.001 | 0.6809 | 0.6776 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.267 | uM | 10124.001 | 0.5825 | 0.5620 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 1.33 | uM | 10124.001 | 0.6701 | 0.6654 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 6.67 | uM | 10124.001 | 0.2842 | 0.1249 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 33.3 | uM | 10124.001 | 0.0057 | -0.8122 | 2.1861 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 10147.001 | 0.9920 | 0.9937 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 10147.001 | 0.9525 | 0.9620 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 10147.001 | 0.9704 | 0.9764 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 10147.001 | 0.9133 | 0.9296 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 10147.001 | 0.3767 | 0.3599 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.267 | uM | 10147.001 | 0.3358 | 0.2996 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 1.33 | uM | 10147.001 | 0.4100 | 0.4062 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 6.67 | uM | 10147.001 | 0.0972 | -0.2036 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 33.3 | uM | 10147.001 | 0.0077 | -0.7068 | 2.5313 | |
| Hs 578T | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7863.001 | 0.9810 | 0.9782 | 1.7540 |