Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 10472.1 | 1.0109 | 1.0345 | 0.6324 | |
| MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 10472.1 | 1.0244 | 1.0778 | 0.6324 | |
| MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 10472.1 | 0.9257 | 0.7701 | 0.6324 | |
| MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 10472.1 | 0.0214 | -0.9954 | 0.6324 | |
| MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 10472.1 | 0.0071 | -0.9992 | 0.6324 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 7515.093 | 0.9232 | 0.8863 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 7515.093 | 0.7959 | 0.6921 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 7515.093 | 0.8771 | 0.8169 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 7515.093 | 0.8810 | 0.8228 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 7515.093 | 0.9212 | 0.8834 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 7515.093 | 0.7603 | 0.6364 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 7515.093 | 0.7928 | 0.6873 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 7515.093 | 0.0077 | -0.9435 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 7515.093 | 0.0074 | -0.9448 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 7516.093 | 1.0034 | 1.0052 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 7516.093 | 0.9133 | 0.8668 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 7516.093 | 0.9571 | 0.9344 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 7516.093 | 0.9688 | 0.9524 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 7516.093 | 0.9655 | 0.9473 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 7516.093 | 0.9959 | 0.9937 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 7516.093 | 0.7673 | 0.6350 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 7516.093 | 0.0102 | -0.9389 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 7516.093 | 0.0066 | -0.9563 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 7517.093 | 0.9692 | 0.9583 | 1.4869 | |
| MDA-MB-453 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 7517.093 | 0.9721 | 0.9623 | 1.4869 |