Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 10519.1 | 0.9548 | 0.9102 | 1.0071 | |
MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 10519.1 | 0.0129 | -0.9735 | 1.0071 | |
MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 10519.1 | 0.0076 | -0.9842 | 1.0071 | |
MDA-MB-157 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000171 | uM | 7496.093 | 1.0049 | 1.0100 | 0.9777 | |
MDA-MB-157 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000853 | uM | 7496.093 | 0.9874 | 0.9743 | 0.9777 | |
MDA-MB-157 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.00427 | uM | 7496.093 | 0.9897 | 0.9789 | 0.9777 | |
MDA-MB-157 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.0213 | uM | 7496.093 | 0.9805 | 0.9600 | 0.9777 | |
MDA-MB-157 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.107 | uM | 7496.093 | 1.0177 | 1.0362 | 0.9777 | |
MDA-MB-157 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.533 | uM | 7496.093 | 0.9658 | 0.9300 | 0.9777 | |
MDA-MB-157 | TNBC | Basal B | IKK16 | IKK | NFKB | 2.67 | uM | 7496.093 | 0.5642 | 0.1138 | 0.9777 | |
MDA-MB-157 | TNBC | Basal B | IKK16 | IKK | NFKB | 13.3 | uM | 7496.093 | 0.0096 | -0.9828 | 0.9777 | |
MDA-MB-157 | TNBC | Basal B | IKK16 | IKK | NFKB | 66.7 | uM | 7496.093 | 0.0099 | -0.9821 | 0.9777 | |
MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 7506.093 | 1.0375 | 1.0819 | 0.9162 | |
MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 7506.093 | 1.0569 | 1.1245 | 0.9162 | |
MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 7506.093 | 1.0401 | 1.0878 | 0.9162 | |
MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 7506.093 | 1.1095 | 1.2403 | 0.9162 | |
MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 7506.093 | 1.0446 | 1.0975 | 0.9162 | |
MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 7506.093 | 1.0158 | 1.0345 | 0.9162 | |
MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 7506.093 | 1.0612 | 1.1341 | 0.9162 | |
MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 7506.093 | 0.0159 | -0.9783 | 0.9162 | |
MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 7506.093 | 0.0101 | -0.9868 | 0.9162 | |
MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 10472.1 | 1.0016 | 1.0051 | 0.6324 | |
MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 10472.1 | 1.0216 | 1.0689 | 0.6324 | |
MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 10472.1 | 0.9228 | 0.7613 | 0.6324 | |
MDA-MB-361 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 10472.1 | 1.0617 | 1.1986 | 0.6324 |