Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MDA-MB-134-VI
HR+
Luminal
IKK16
IKK
NFKB
2.67
uM
10519.1
0.9548 0.9102 1.0071
MDA-MB-134-VI
HR+
Luminal
IKK16
IKK
NFKB
13.3
uM
10519.1
0.0129 -0.9735 1.0071
MDA-MB-134-VI
HR+
Luminal
IKK16
IKK
NFKB
66.7
uM
10519.1
0.0076 -0.9842 1.0071
MDA-MB-157
TNBC
Basal B
IKK16
IKK
NFKB
0.000171
uM
7496.093
1.0049 1.0100 0.9777
MDA-MB-157
TNBC
Basal B
IKK16
IKK
NFKB
0.000853
uM
7496.093
0.9874 0.9743 0.9777
MDA-MB-157
TNBC
Basal B
IKK16
IKK
NFKB
0.00427
uM
7496.093
0.9897 0.9789 0.9777
MDA-MB-157
TNBC
Basal B
IKK16
IKK
NFKB
0.0213
uM
7496.093
0.9805 0.9600 0.9777
MDA-MB-157
TNBC
Basal B
IKK16
IKK
NFKB
0.107
uM
7496.093
1.0177 1.0362 0.9777
MDA-MB-157
TNBC
Basal B
IKK16
IKK
NFKB
0.533
uM
7496.093
0.9658 0.9300 0.9777
MDA-MB-157
TNBC
Basal B
IKK16
IKK
NFKB
2.67
uM
7496.093
0.5642 0.1138 0.9777
MDA-MB-157
TNBC
Basal B
IKK16
IKK
NFKB
13.3
uM
7496.093
0.0096 -0.9828 0.9777
MDA-MB-157
TNBC
Basal B
IKK16
IKK
NFKB
66.7
uM
7496.093
0.0099 -0.9821 0.9777
MDA-MB-361
HER2amp
Luminal
IKK16
IKK
NFKB
0.000171
uM
7506.093
1.0375 1.0819 0.9162
MDA-MB-361
HER2amp
Luminal
IKK16
IKK
NFKB
0.000853
uM
7506.093
1.0569 1.1245 0.9162
MDA-MB-361
HER2amp
Luminal
IKK16
IKK
NFKB
0.00427
uM
7506.093
1.0401 1.0878 0.9162
MDA-MB-361
HER2amp
Luminal
IKK16
IKK
NFKB
0.0213
uM
7506.093
1.1095 1.2403 0.9162
MDA-MB-361
HER2amp
Luminal
IKK16
IKK
NFKB
0.107
uM
7506.093
1.0446 1.0975 0.9162
MDA-MB-361
HER2amp
Luminal
IKK16
IKK
NFKB
0.533
uM
7506.093
1.0158 1.0345 0.9162
MDA-MB-361
HER2amp
Luminal
IKK16
IKK
NFKB
2.67
uM
7506.093
1.0612 1.1341 0.9162
MDA-MB-361
HER2amp
Luminal
IKK16
IKK
NFKB
13.3
uM
7506.093
0.0159 -0.9783 0.9162
MDA-MB-361
HER2amp
Luminal
IKK16
IKK
NFKB
66.7
uM
7506.093
0.0101 -0.9868 0.9162
MDA-MB-361
HER2amp
Luminal
IKK16
IKK
NFKB
0.000171
uM
10472.1
1.0016 1.0051 0.6324
MDA-MB-361
HER2amp
Luminal
IKK16
IKK
NFKB
0.000853
uM
10472.1
1.0216 1.0689 0.6324
MDA-MB-361
HER2amp
Luminal
IKK16
IKK
NFKB
0.00427
uM
10472.1
0.9228 0.7613 0.6324
MDA-MB-361
HER2amp
Luminal
IKK16
IKK
NFKB
0.0213
uM
10472.1
1.0617 1.1986 0.6324