Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10F | NM | - | IKK16 | IKK | NFKB | 66.7 | uM | 7486.1 | 0.0005 | -0.9988 | 1.0281 | |
| MCF12A | NM | Basal B | IKK16 | IKK | NFKB | 0.000171 | uM | 7490.093 | 0.9878 | 0.9897 | 2.3707 | |
| MCF12A | NM | Basal B | IKK16 | IKK | NFKB | 0.000853 | uM | 7490.093 | 0.9355 | 0.9446 | 2.3707 | |
| MCF12A | NM | Basal B | IKK16 | IKK | NFKB | 0.00427 | uM | 7490.093 | 0.9754 | 0.9791 | 2.3707 | |
| MCF12A | NM | Basal B | IKK16 | IKK | NFKB | 0.0213 | uM | 7490.093 | 0.9984 | 0.9987 | 2.3707 | |
| MCF12A | NM | Basal B | IKK16 | IKK | NFKB | 0.107 | uM | 7490.093 | 0.9719 | 0.9761 | 2.3707 | |
| MCF12A | NM | Basal B | IKK16 | IKK | NFKB | 0.533 | uM | 7490.093 | 0.9459 | 0.9536 | 2.3707 | |
| MCF12A | NM | Basal B | IKK16 | IKK | NFKB | 2.67 | uM | 7490.093 | 0.7798 | 0.8008 | 2.3707 | |
| MCF12A | NM | Basal B | IKK16 | IKK | NFKB | 13.3 | uM | 7490.093 | 0.0106 | -0.7067 | 2.3707 | |
| MCF12A | NM | Basal B | IKK16 | IKK | NFKB | 66.7 | uM | 7490.093 | 0.0099 | -0.7142 | 2.3707 | |
| MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 10419.093 | 1.0354 | 1.1255 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 10419.093 | 1.0138 | 1.0486 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 10419.093 | 1.0425 | 1.1509 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 10419.093 | 1.0166 | 1.0584 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 10419.093 | 1.0291 | 1.1027 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 10419.093 | 1.0261 | 1.0923 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 10419.093 | 1.0036 | 1.0126 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 10419.093 | 0.1848 | -0.8956 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 10419.093 | 0.0077 | -0.9996 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 10519.1 | 1.0164 | 1.0327 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 10519.1 | 0.9658 | 0.9321 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 10519.1 | 0.9899 | 0.9800 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 10519.1 | 1.0698 | 1.1385 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 10519.1 | 1.0226 | 1.0448 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 10519.1 | 0.9749 | 0.9501 | 1.0071 |