Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 9210.001 | 0.5112 | -0.0702 | 0.8761 | |
| CAMA-1 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 9210.001 | 0.5649 | 0.0422 | 0.8761 | |
| CAMA-1 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 9210.001 | 0.5766 | 0.0667 | 0.8761 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7808.001 | 1.0014 | 1.0011 | 2.5321 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7808.001 | 0.9057 | 0.9233 | 2.5321 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7808.001 | 1.1455 | 1.1102 | 2.5321 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7808.001 | 0.9745 | 0.9797 | 2.5321 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7808.001 | 0.5250 | 0.5507 | 2.5321 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7808.001 | 0.3169 | 0.2703 | 2.5321 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7808.001 | 0.2848 | 0.2180 | 2.5321 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7808.001 | 0.3040 | 0.2497 | 2.5321 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7808.001 | 0.1522 | -0.0490 | 2.5321 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 9226.001 | 0.9788 | 0.9839 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 9226.001 | 0.9178 | 0.9365 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 9226.001 | 1.0041 | 1.0031 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 9226.001 | 0.9773 | 0.9828 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 9226.001 | 0.3927 | 0.4068 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 0.267 | uM | 9226.001 | 0.2682 | 0.2188 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 1.33 | uM | 9226.001 | 0.3049 | 0.2790 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 6.67 | uM | 9226.001 | 0.3349 | 0.3250 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK923295 | CENPE | Kinesin | 33.3 | uM | 9226.001 | 0.2254 | 0.1416 | 2.6569 | |
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7810.001 | 1.0597 | 1.1322 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7810.001 | 1.0406 | 1.0898 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7810.001 | 1.0008 | 1.0018 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7810.001 | 0.9834 | 0.9635 | 0.9063 |