Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7810.001 | 0.7429 | 0.4409 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7810.001 | 0.5352 | 0.0034 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7810.001 | 0.5823 | 0.1013 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7810.001 | 0.5670 | 0.0694 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7810.001 | 0.3031 | -0.4641 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 9233.001 | 1.0813 | 1.1654 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 9233.001 | 0.9556 | 0.9099 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 9233.001 | 1.0451 | 1.0917 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 9233.001 | 0.9907 | 0.9810 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 9233.001 | 0.7622 | 0.5176 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.267 | uM | 9233.001 | 0.6648 | 0.3207 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 1.33 | uM | 9233.001 | 0.6396 | 0.2699 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 6.67 | uM | 9233.001 | 0.6310 | 0.2524 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 33.3 | uM | 9233.001 | 0.4277 | -0.1564 | 0.9839 | |
| HCC1187 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7811.001 | 0.9745 | 0.8876 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7811.001 | 0.9582 | 0.8177 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7811.001 | 0.9566 | 0.8109 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7811.001 | 1.0196 | 1.0890 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7811.001 | 0.2146 | -0.9363 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7811.001 | 0.0807 | -0.9929 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7811.001 | 0.0680 | -0.9951 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7811.001 | 0.0843 | -0.9922 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7811.001 | 0.1673 | -0.9635 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7812.001 | 1.0311 | 1.0618 | 1.0060 | |
| HCC1187 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7812.001 | 1.0347 | 1.0691 | 1.0060 |