Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 33.3 | uM | 7926.001 | 0.6338 | 0.1190 | 0.7852 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 9913.001 | 1.1080 | 1.8001 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.000427 | uM | 9913.001 | 1.1961 | 2.5993 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.00213 | uM | 9913.001 | 1.0525 | 1.3660 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0107 | uM | 9913.001 | 1.0368 | 1.2520 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0533 | uM | 9913.001 | 1.0911 | 1.6628 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.267 | uM | 9913.001 | 1.1767 | 2.4115 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 1.33 | uM | 9913.001 | 0.9993 | 0.9957 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 6.67 | uM | 9913.001 | 1.0381 | 1.2610 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 33.3 | uM | 9913.001 | 0.2335 | -0.9831 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 10150.001 | 1.0545 | 1.3539 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.000427 | uM | 10150.001 | 1.1612 | 2.1651 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.00213 | uM | 10150.001 | 0.9838 | 0.9022 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0107 | uM | 10150.001 | 1.0511 | 1.3309 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0533 | uM | 10150.001 | 0.8261 | 0.1120 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.267 | uM | 10150.001 | 1.1500 | 2.0725 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 1.33 | uM | 10150.001 | 0.9956 | 0.9729 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 6.67 | uM | 10150.001 | 0.9917 | 0.9493 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 33.3 | uM | 10150.001 | 0.2869 | -0.9569 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 10151.001 | 1.0377 | 1.1838 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.000427 | uM | 10151.001 | 1.1079 | 1.5508 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.00213 | uM | 10151.001 | 1.0679 | 1.3374 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0107 | uM | 10151.001 | 1.0042 | 1.0199 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0533 | uM | 10151.001 | 0.8359 | 0.3066 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.267 | uM | 10151.001 | 1.0416 | 1.2031 | 0.4212 |