Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.000427 | uM | 7899.001 | 1.0886 | 1.0848 | 2.0444 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.00213 | uM | 7899.001 | 0.8270 | 0.8225 | 2.0444 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0107 | uM | 7899.001 | 0.6538 | 0.6246 | 2.0444 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0533 | uM | 7899.001 | 0.4897 | 0.4104 | 2.0444 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.267 | uM | 7899.001 | 0.4566 | 0.3629 | 2.0444 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 1.33 | uM | 7899.001 | 0.5381 | 0.4769 | 2.0444 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 6.67 | uM | 7899.001 | 0.5457 | 0.4872 | 2.0444 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 33.3 | uM | 7899.001 | 0.4551 | 0.3607 | 2.0444 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 7900.001 | 1.0188 | 1.0475 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.000427 | uM | 7900.001 | 1.2475 | 1.6420 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.00213 | uM | 7900.001 | 0.8189 | 0.5552 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0107 | uM | 7900.001 | 1.0608 | 1.1543 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0533 | uM | 7900.001 | 0.5902 | 0.0298 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.267 | uM | 7900.001 | 0.5026 | -0.1588 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 1.33 | uM | 7900.001 | 0.6400 | 0.1403 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 6.67 | uM | 7900.001 | 0.4694 | -0.2281 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 33.3 | uM | 7900.001 | 0.3148 | -0.5333 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 7902.001 | 0.9705 | 0.9693 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.000427 | uM | 7902.001 | 1.1599 | 1.1593 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.00213 | uM | 7902.001 | 0.7166 | 0.6837 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0107 | uM | 7902.001 | 0.5005 | 0.3988 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0533 | uM | 7902.001 | 0.4665 | 0.3489 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.267 | uM | 7902.001 | 0.4467 | 0.3191 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 1.33 | uM | 7902.001 | 0.6076 | 0.5462 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 6.67 | uM | 7902.001 | 0.6022 | 0.5391 | 1.9359 |