Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 11852.143 | 0.3638 | -0.1219 | 1.2284 | ||
| T47D | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 10939.143 | 0.9956 | 0.9950 | 1.7568 | ||
| T47D | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 10939.143 | 0.9300 | 0.9191 | 1.7568 | ||
| T47D | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 10939.143 | 0.9963 | 0.9958 | 1.7568 | ||
| T47D | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 10939.143 | 1.0393 | 1.0443 | 1.7568 | ||
| T47D | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 10939.143 | 0.9486 | 0.9408 | 1.7568 | ||
| T47D | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 10939.143 | 0.8881 | 0.8693 | 1.7568 | ||
| T47D | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 10939.143 | 0.4803 | 0.3174 | 1.7568 | ||
| T47D | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 10939.143 | 0.3727 | 0.1403 | 1.7568 | ||
| T47D | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 10939.143 | 0.3786 | 0.1505 | 1.7568 | ||
| T47DKBLUC | Unknown | Unknown | Ibandronate | FDPS | 0.00384 | uM | 12608.143 | 1.0103 | 1.0183 | 1.1322 | ||
| T47DKBLUC | Unknown | Unknown | Ibandronate | FDPS | 0.0192 | uM | 12608.143 | 0.9711 | 0.9488 | 1.1322 | ||
| T47DKBLUC | Unknown | Unknown | Ibandronate | FDPS | 0.096 | uM | 12608.143 | 1.0126 | 1.0222 | 1.1322 | ||
| T47DKBLUC | Unknown | Unknown | Ibandronate | FDPS | 0.48 | uM | 12608.143 | 1.0451 | 1.0795 | 1.1322 | ||
| T47DKBLUC | Unknown | Unknown | Ibandronate | FDPS | 2.4 | uM | 12608.143 | 1.0309 | 1.0546 | 1.1322 | ||
| T47DKBLUC | Unknown | Unknown | Ibandronate | FDPS | 12 | uM | 12608.143 | 1.0341 | 1.0601 | 1.1322 | ||
| T47DKBLUC | Unknown | Unknown | Ibandronate | FDPS | 60 | uM | 12608.143 | 0.8899 | 0.8042 | 1.1322 | ||
| T47DKBLUC | Unknown | Unknown | Ibandronate | FDPS | 300 | uM | 12608.143 | 0.4779 | 0.0418 | 1.1322 | ||
| T47DKBLUC | Unknown | Unknown | Ibandronate | FDPS | 1500 | uM | 12608.143 | 0.4446 | -0.0226 | 1.1322 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 0.00384 | uM | 10580.143 | 1.0249 | 1.0594 | 0.8402 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 0.0192 | uM | 10580.143 | 0.9008 | 0.7662 | 0.8402 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 0.096 | uM | 10580.143 | 0.9593 | 0.9035 | 0.8402 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 0.48 | uM | 10580.143 | 0.9602 | 0.9056 | 0.8402 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 2.4 | uM | 10580.143 | 0.9668 | 0.9212 | 0.8402 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 12 | uM | 10580.143 | 0.9520 | 0.8863 | 0.8402 |