Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7526.091 | 0.8657 | 0.8347 | 1.6709 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7526.091 | 0.0276 | -0.7665 | 1.6709 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7526.091 | 0.7376 | 0.6670 | 1.6709 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7526.098 | 0.9496 | 0.9334 | 1.5260 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7526.098 | 0.9507 | 0.9348 | 1.5260 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7526.098 | 0.9635 | 0.9519 | 1.5260 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7526.098 | 0.9832 | 0.9780 | 1.5260 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7526.098 | 0.9409 | 0.9218 | 1.5260 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7526.098 | 0.9658 | 0.9549 | 1.5260 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7526.098 | 0.9984 | 0.9979 | 1.5260 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7526.098 | 0.9388 | 0.9189 | 1.5260 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7526.098 | 0.8333 | 0.7747 | 1.5260 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7527.092 | 0.9993 | 0.9993 | 2.0383 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7527.092 | 0.9555 | 0.9558 | 2.0383 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7527.092 | 0.9688 | 0.9691 | 2.0383 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7527.092 | 1.0229 | 1.0223 | 2.0383 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7527.092 | 1.0012 | 1.0012 | 2.0383 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7527.092 | 0.9400 | 0.9402 | 2.0383 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7527.092 | 0.8564 | 0.8536 | 2.0383 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7527.092 | 0.0981 | -0.3598 | 2.0383 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7527.092 | 0.0458 | -0.5593 | 2.0383 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7527.098 | 0.9308 | 0.9186 | 1.7263 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7527.098 | 0.9983 | 0.9980 | 1.7263 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7527.098 | 1.0231 | 1.0266 | 1.7263 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7527.098 | 1.0201 | 1.0232 | 1.7263 |