Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7506.091 | 1.0450 | 1.0809 | 1.1096 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7507.07 | 1.0506 | 1.1006 | 1.0062 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7507.07 | 1.0351 | 1.0697 | 1.0062 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7507.07 | 0.9712 | 0.9428 | 1.0062 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7507.07 | 1.0007 | 1.0014 | 1.0062 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7507.07 | 0.9691 | 0.9385 | 1.0062 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7507.07 | 0.9924 | 0.9849 | 1.0062 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7507.07 | 0.9607 | 0.9219 | 1.0062 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7507.07 | 0.7846 | 0.5716 | 1.0062 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7507.07 | 0.0270 | -0.9449 | 1.0062 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7507.09 | 1.0252 | 1.0499 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7507.09 | 1.0088 | 1.0174 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7507.09 | 1.0274 | 1.0542 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7507.09 | 1.0371 | 1.0733 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7507.09 | 1.0083 | 1.0164 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7507.09 | 0.9870 | 0.9742 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7507.09 | 0.9222 | 0.8461 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7507.09 | 1.0332 | 1.0657 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7507.09 | 0.9793 | 0.9591 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7507.098 | 0.9944 | 0.9890 | 1.0164 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7507.098 | 0.9517 | 0.9049 | 1.0164 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7507.098 | 0.9632 | 0.9276 | 1.0164 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7507.098 | 0.9545 | 0.9105 | 1.0164 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7507.098 | 0.9802 | 0.9611 | 1.0164 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7507.098 | 0.9590 | 0.9192 | 1.0164 |