Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	2.67	uM	7507.098	0.9429	0.8877	1.0164
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	13.3	uM	7507.098	0.6993	0.4068	1.0164
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	66.7	uM	7507.098	0.0220	-0.9532	1.0164
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	0.000307	uM	7508.071	1.0348	1.0835	0.8372
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	0.00154	uM	7508.071	0.9595	0.9035	0.8372
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	0.00768	uM	7508.071	0.9349	0.8454	0.8372
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	0.0384	uM	7508.071	0.9326	0.8400	0.8372
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	0.192	uM	7508.071	0.9725	0.9346	0.8372
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	0.96	uM	7508.071	0.9767	0.9444	0.8372
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	4.8	uM	7508.071	0.8705	0.6947	0.8372
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	24	uM	7508.071	0.0147	-0.9870	0.8372
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	120	uM	7508.071	0.0116	-0.9903	0.8372
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	0.000341	uM	7508.091	0.9982	0.9946	0.6662
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	0.00171	uM	7508.091	0.9908	0.9726	0.6662
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	0.00853	uM	7508.091	0.9609	0.8836	0.6662
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	0.0427	uM	7508.091	1.0235	1.0709	0.6662
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	0.213	uM	7508.091	0.9372	0.8145	0.6662
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	1.07	uM	7508.091	0.9405	0.8242	0.6662
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	5.33	uM	7508.091	0.9396	0.8213	0.6662
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	26.7	uM	7508.091	0.9668	0.9012	0.6662
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	133	uM	7508.091	0.0138	-0.9968	0.6662
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	0.000171	uM	7508.098	1.0090	1.0225	0.7973
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	0.000853	uM	7508.098	1.0096	1.0240	0.7973
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	0.00427	uM	7508.098	0.9911	0.9777	0.7973
MDA-MB-361	HER2amp	Luminal	GSK1838705A	IGF1R	RTK	0.0213	uM	7508.098	0.9590	0.8977	0.7973

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)