Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7508.098 | 1.0113 | 1.0283 | 0.7973 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7508.098 | 1.0248 | 1.0624 | 0.7973 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7508.098 | 0.9250 | 0.8137 | 0.7973 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7508.098 | 0.9725 | 0.9312 | 0.7973 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7508.098 | 0.8855 | 0.7171 | 0.7973 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7510.07 | 0.9523 | 0.8828 | 0.8102 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7510.07 | 1.0282 | 1.0699 | 0.8102 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7510.07 | 0.9300 | 0.8286 | 0.8102 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7510.07 | 0.9437 | 0.8620 | 0.8102 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7510.07 | 0.9872 | 0.9684 | 0.8102 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7510.07 | 0.9526 | 0.8837 | 0.8102 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7510.07 | 0.9224 | 0.8101 | 0.8102 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7510.07 | 0.0210 | -0.9830 | 0.8102 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7510.07 | 0.0232 | -0.9808 | 0.8102 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7510.09 | 0.9209 | 0.8552 | 1.0960 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7510.09 | 0.9508 | 0.9100 | 1.0960 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7510.09 | 1.0094 | 1.0172 | 1.0960 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7510.09 | 0.8755 | 0.7716 | 1.0960 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7510.09 | 0.8335 | 0.6938 | 1.0960 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7510.09 | 0.9420 | 0.8938 | 1.0960 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7510.09 | 0.6924 | 0.4301 | 1.0960 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7510.09 | 0.7634 | 0.5633 | 1.0960 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7510.09 | 0.6316 | 0.3151 | 1.0960 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7510.098 | 1.0281 | 1.0590 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7510.098 | 1.0103 | 1.0215 | 0.9528 |