Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7492.091 | 0.4701 | 0.1900 | 1.4539 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7492.091 | 0.0333 | -0.8072 | 1.4539 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7492.091 | 0.1975 | -0.3446 | 1.4539 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7492.098 | 1.0279 | 1.0354 | 1.5701 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7492.098 | 0.9864 | 0.9826 | 1.5701 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7492.098 | 0.9874 | 0.9839 | 1.5701 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7492.098 | 0.9552 | 0.9425 | 1.5701 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7492.098 | 0.9589 | 0.9473 | 1.5701 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7492.098 | 0.8793 | 0.8427 | 1.5701 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7492.098 | 0.5282 | 0.3319 | 1.5701 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7492.098 | 0.5765 | 0.4083 | 1.5701 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7492.098 | 0.3797 | 0.0794 | 1.5701 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7493.091 | 1.0258 | 1.0474 | 1.0859 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7493.091 | 0.9935 | 0.9880 | 1.0859 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7493.091 | 1.0285 | 1.0524 | 1.0859 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7493.091 | 1.0285 | 1.0524 | 1.0859 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7493.091 | 1.0079 | 1.0145 | 1.0859 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7493.091 | 0.5636 | 0.1795 | 1.0859 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7493.091 | 0.3433 | -0.2529 | 1.0859 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7493.091 | 0.0286 | -0.9243 | 1.0859 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7493.091 | 0.0220 | -0.9404 | 1.0859 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7493.098 | 0.9395 | 0.8796 | 1.0051 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7493.098 | 0.9396 | 0.8798 | 1.0051 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7493.098 | 1.0125 | 1.0248 | 1.0051 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7493.098 | 1.0006 | 1.0011 | 1.0051 |