Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7473.098 | 2.0478 | 1.7384 | 2.2810 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7474.071 | 1.1531 | 1.1105 | 2.6483 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7474.071 | 1.3393 | 1.2332 | 2.6483 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7474.071 | 0.9604 | 0.9698 | 2.6483 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7474.071 | 1.0330 | 1.0247 | 2.6483 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7474.071 | 1.1834 | 1.1313 | 2.6483 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7474.071 | 1.2124 | 1.1509 | 2.6483 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7474.071 | 1.4435 | 1.2974 | 2.6483 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 24 | uM | 7474.071 | 0.7780 | 0.8191 | 2.6483 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 120 | uM | 7474.071 | 0.3836 | 0.3928 | 2.6483 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7474.09 | 1.0403 | 1.0327 | 2.4405 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7474.09 | 0.9922 | 0.9936 | 2.4405 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7474.09 | 1.0021 | 1.0018 | 2.4405 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7474.09 | 0.9589 | 0.9659 | 2.4405 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7474.09 | 1.0750 | 1.0601 | 2.4405 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7474.09 | 1.4757 | 1.3457 | 2.4405 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7474.09 | 1.1564 | 1.1227 | 2.4405 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7474.09 | 1.0771 | 1.0618 | 2.4405 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 133 | uM | 7474.09 | 0.9476 | 0.9564 | 2.4405 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7474.098 | 1.0332 | 1.0252 | 2.6093 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7474.098 | 1.0339 | 1.0258 | 2.6093 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7474.098 | 0.8905 | 0.9131 | 2.6093 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7474.098 | 0.9632 | 0.9715 | 2.6093 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7474.098 | 1.0294 | 1.0223 | 2.6093 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7474.098 | 1.0057 | 1.0044 | 2.6093 |