Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7493.098 | 0.9348 | 0.8703 | 1.0051 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7493.098 | 0.7220 | 0.4464 | 1.0051 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7493.098 | 0.4317 | -0.1330 | 1.0051 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7493.098 | 0.1214 | -0.7546 | 1.0051 | |
| MCF7 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7493.098 | 0.0231 | -0.9530 | 1.0051 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7494.07 | 0.9127 | 0.8148 | 0.9405 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7494.07 | 0.9365 | 0.8653 | 0.9405 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7494.07 | 0.9266 | 0.8442 | 0.9405 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7494.07 | 0.9366 | 0.8655 | 0.9405 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7494.07 | 0.9281 | 0.8475 | 0.9405 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7494.07 | 0.9042 | 0.7969 | 0.9405 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7494.07 | 0.9418 | 0.8764 | 0.9405 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7494.07 | 0.4578 | -0.1286 | 0.9405 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7494.07 | 0.0168 | -0.9740 | 0.9405 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7494.09 | 0.9700 | 0.9446 | 1.0823 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7494.09 | 0.8847 | 0.7859 | 1.0823 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7494.09 | 0.9726 | 0.9494 | 1.0823 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7494.09 | 0.9434 | 0.8952 | 1.0823 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7494.09 | 0.8784 | 0.7742 | 1.0823 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7494.09 | 0.8664 | 0.7517 | 1.0823 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7494.09 | 0.8237 | 0.6719 | 1.0823 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7494.09 | 0.8865 | 0.7893 | 1.0823 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7494.09 | 0.8236 | 0.6716 | 1.0823 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7494.098 | 0.9591 | 0.9162 | 0.9748 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7494.098 | 0.9931 | 0.9859 | 0.9748 |