Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7848.001 | 1.0766 | 1.3521 | 0.4548 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7848.001 | 0.9679 | 0.8616 | 0.4548 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7848.001 | 0.9487 | 0.7813 | 0.4548 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7848.001 | 0.5596 | -0.4419 | 0.4548 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7848.001 | 0.6007 | -0.3478 | 0.4548 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7848.001 | 0.6396 | -0.2513 | 0.4548 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7848.001 | 0.5196 | -0.5258 | 0.4548 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7849.001 | 1.0224 | 1.0851 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7849.001 | 1.0157 | 1.0597 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7849.001 | 1.0415 | 1.1591 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7849.001 | 1.0014 | 1.0055 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7849.001 | 0.9708 | 0.8913 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7849.001 | 0.5720 | -0.3019 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7849.001 | 0.6348 | -0.1504 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7849.001 | 0.6646 | -0.0738 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7849.001 | 0.5187 | -0.4193 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 9420.001 | 0.9640 | 0.7918 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 9420.001 | 0.9707 | 0.8291 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 9420.001 | 1.0125 | 1.0760 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 9420.001 | 0.9667 | 0.8067 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 9420.001 | 0.7443 | -0.1756 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 9420.001 | 0.5886 | -0.5923 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 9420.001 | 0.6393 | -0.4776 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 9420.001 | 0.6537 | -0.4415 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 9420.001 | 0.6204 | -0.5226 | 0.3332 |