Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 10263.001 | 1.0032 | 1.0196 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 10263.001 | 0.9145 | 0.5203 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 10263.001 | 1.0381 | 1.2430 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 10263.001 | 0.9941 | 0.9639 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 10263.001 | 0.7303 | -0.2378 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 10263.001 | 0.4225 | -0.8578 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 10263.001 | 0.5235 | -0.7256 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 10263.001 | 0.6394 | -0.4932 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 10263.001 | 0.6141 | -0.5522 | 0.3258 | |
| HCC3153 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7853.001 | 0.9578 | 0.9461 | 1.5775 | |
| HCC3153 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7853.001 | 0.9705 | 0.9625 | 1.5775 | |
| HCC3153 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7853.001 | 1.0097 | 1.0123 | 1.5775 | |
| HCC3153 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7853.001 | 0.9877 | 0.9844 | 1.5775 | |
| HCC3153 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7853.001 | 0.8584 | 0.8155 | 1.5775 | |
| HCC3153 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7853.001 | 0.2850 | -0.0975 | 1.5775 | |
| HCC3153 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7853.001 | 0.2912 | -0.0850 | 1.5775 | |
| HCC3153 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7853.001 | 0.2829 | -0.1016 | 1.5775 | |
| HCC3153 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7853.001 | 0.2739 | -0.1199 | 1.5775 | |
| HCC3153 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 10056.001 | 0.9668 | 0.9267 | 0.9052 | |
| HCC3153 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 10056.001 | 0.9644 | 0.9214 | 0.9052 | |
| HCC3153 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 10056.001 | 1.0053 | 1.0117 | 0.9052 | |
| HCC3153 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 10056.001 | 0.9940 | 0.9869 | 0.9052 | |
| HCC3153 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 10056.001 | 0.8280 | 0.6235 | 0.9052 | |
| HCC3153 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.267 | uM | 10056.001 | 0.4540 | -0.1641 | 0.9052 | |
| HCC3153 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 1.33 | uM | 10056.001 | 0.4489 | -0.1744 | 0.9052 |