Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7474.098 | 1.5415 | 1.3608 | 2.6093 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7474.098 | 0.1050 | -0.1570 | 2.6093 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7474.098 | 0.0743 | -0.2613 | 2.6093 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7475.07 | 0.9776 | 0.9835 | 2.7378 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7475.07 | 1.1128 | 1.0796 | 2.7378 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7475.07 | 1.0462 | 1.0333 | 2.7378 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7475.07 | 0.9794 | 0.9849 | 2.7378 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7475.07 | 1.0376 | 1.0271 | 2.7378 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7475.07 | 1.0110 | 1.0080 | 2.7378 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7475.07 | 1.3458 | 1.2291 | 2.7378 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7475.07 | 0.4490 | 0.4928 | 2.7378 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7475.07 | 1.3393 | 1.2252 | 2.7378 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7475.091 | 1.2406 | 1.1673 | 2.6839 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7475.091 | 1.2583 | 1.1787 | 2.6839 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7475.091 | 1.1301 | 1.0932 | 2.6839 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7475.091 | 1.4577 | 1.3015 | 2.6839 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7475.091 | 1.2527 | 1.1751 | 2.6839 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7475.091 | 1.3413 | 1.2312 | 2.6839 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7475.091 | 0.6126 | 0.6662 | 2.6839 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7475.091 | 1.8321 | 1.5062 | 2.6839 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 133 | uM | 7475.091 | 1.1465 | 1.1045 | 2.6839 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7475.098 | 1.0338 | 1.0293 | 2.2876 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7475.098 | 1.1060 | 1.0900 | 2.2876 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7475.098 | 1.0766 | 1.0656 | 2.2876 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7475.098 | 1.1321 | 1.1114 | 2.2876 |