Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7494.098 | 0.9437 | 0.8845 | 0.9748 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7494.098 | 0.9327 | 0.8620 | 0.9748 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7494.098 | 0.9441 | 0.8854 | 0.9748 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7494.098 | 0.9891 | 0.9776 | 0.9748 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7494.098 | 0.9108 | 0.8172 | 0.9748 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7494.098 | 0.4480 | -0.1223 | 0.9748 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7494.098 | 0.0171 | -0.9693 | 0.9748 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7495.098 | 1.1049 | 1.3724 | 0.5841 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7495.098 | 0.7542 | 0.2338 | 0.5841 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7495.098 | 1.2075 | 1.7618 | 0.5841 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7495.098 | 1.0573 | 1.2000 | 0.5841 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7495.098 | 1.1711 | 1.6211 | 0.5841 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7495.098 | 0.8476 | 0.5070 | 0.5841 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7495.098 | 0.8623 | 0.5518 | 0.5841 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7495.098 | 0.7818 | 0.3121 | 0.5841 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7495.098 | 0.1255 | -0.9427 | 0.5841 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7496.092 | 1.0216 | 1.0438 | 0.9861 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7496.092 | 0.9704 | 0.9399 | 0.9861 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7496.092 | 0.9818 | 0.9630 | 0.9861 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7496.092 | 0.9862 | 0.9719 | 0.9861 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7496.092 | 0.9976 | 0.9952 | 0.9861 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7496.092 | 0.9553 | 0.9093 | 0.9861 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7496.092 | 0.9471 | 0.8926 | 0.9861 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7496.092 | 0.5599 | 0.1107 | 0.9861 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7496.092 | 0.0909 | -0.8243 | 0.9861 |