Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 133 | uM | 7523.091 | 0.0136 | -0.9805 | 0.9283 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7523.098 | 1.0859 | 1.1940 | 0.8897 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7523.098 | 1.0025 | 1.0056 | 0.8897 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7523.098 | 1.0132 | 1.0298 | 0.8897 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7523.098 | 0.9999 | 0.9997 | 0.8897 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7523.098 | 0.9679 | 0.9279 | 0.8897 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7523.098 | 0.9581 | 0.9061 | 0.8897 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7523.098 | 0.9422 | 0.8706 | 0.8897 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7523.098 | 0.0482 | -0.9338 | 0.8897 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7523.098 | 0.8705 | 0.7113 | 0.8897 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7526.071 | 1.2797 | 1.4444 | 1.2290 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7526.071 | 1.2438 | 1.3884 | 1.2290 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7526.071 | 1.2685 | 1.4270 | 1.2290 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7526.071 | 1.2922 | 1.4639 | 1.2290 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7526.071 | 1.2596 | 1.4132 | 1.2290 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7526.071 | 1.3156 | 1.5002 | 1.2290 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7526.071 | 1.2821 | 1.4482 | 1.2290 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 24 | uM | 7526.071 | 0.4260 | -0.0013 | 1.2290 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 120 | uM | 7526.071 | 1.1025 | 1.1653 | 1.2290 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7526.091 | 0.9030 | 0.8815 | 1.6709 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7526.091 | 0.9481 | 0.9372 | 1.6709 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7526.091 | 0.9317 | 0.9171 | 1.6709 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7526.091 | 0.9547 | 0.9453 | 1.6709 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7526.091 | 0.9545 | 0.9451 | 1.6709 | |
| SK-BR-3 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7526.091 | 0.9416 | 0.9293 | 1.6709 |