Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7466.098 | 0.9783 | 0.9474 | 0.8226 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7466.098 | 0.9718 | 0.9315 | 0.8226 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7466.098 | 0.9777 | 0.9460 | 0.8226 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7466.098 | 0.8849 | 0.7237 | 0.8226 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7466.098 | 0.8133 | 0.5557 | 0.8226 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7466.098 | 0.6218 | 0.1225 | 0.8226 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7466.098 | 0.5274 | -0.0812 | 0.8226 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7467.071 | 0.9963 | 0.9944 | 1.3411 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7467.071 | 1.0077 | 1.0115 | 1.3411 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7467.071 | 0.9879 | 0.9820 | 1.3411 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7467.071 | 1.0106 | 1.0158 | 1.3411 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7467.071 | 0.9597 | 0.9396 | 1.3411 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7467.071 | 0.9294 | 0.8938 | 1.3411 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7467.071 | 0.8072 | 0.7049 | 1.3411 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 24 | uM | 7467.071 | 0.1096 | -0.6154 | 1.3411 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 120 | uM | 7467.071 | 0.0264 | -0.8670 | 1.3411 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7467.091 | 0.9912 | 0.9865 | 1.2996 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7467.091 | 0.9775 | 0.9653 | 1.2996 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7467.091 | 1.0021 | 1.0032 | 1.2996 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7467.091 | 0.9822 | 0.9725 | 1.2996 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7467.091 | 0.9636 | 0.9437 | 1.2996 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7467.091 | 0.8458 | 0.7581 | 1.2996 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7467.091 | 0.7606 | 0.6203 | 1.2996 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7467.091 | 0.0411 | -0.8283 | 1.2996 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 133 | uM | 7467.091 | 0.0619 | -0.7649 | 1.2996 |