Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7450.071 | 1.2728 | 1.2151 | 2.3612 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7450.071 | 0.9091 | 0.9209 | 2.3612 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7450.071 | 0.8662 | 0.8819 | 2.3612 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 24 | uM | 7450.071 | 0.9022 | 0.9147 | 2.3612 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 120 | uM | 7450.071 | 0.8869 | 0.9009 | 2.3612 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7450.091 | 2.6811 | 4.1536 | 1.0419 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7450.091 | 2.7399 | 4.2620 | 1.0419 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7450.091 | 2.6455 | 4.0878 | 1.0419 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7450.091 | 2.0660 | 3.0130 | 1.0419 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7450.091 | 2.5477 | 3.9072 | 1.0419 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7450.091 | 2.2859 | 3.4222 | 1.0419 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7450.091 | 1.0194 | 1.0372 | 1.0419 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7450.091 | 0.0260 | -0.9398 | 1.0419 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 133 | uM | 7450.091 | 0.0467 | -0.8943 | 1.0419 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7450.098 | 1.0132 | 1.0119 | 2.2139 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7450.098 | 1.0590 | 1.0524 | 2.2139 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7450.098 | 1.0274 | 1.0246 | 2.2139 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7450.098 | 1.0324 | 1.0290 | 2.2139 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7450.098 | 0.9793 | 0.9812 | 2.2139 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7450.098 | 1.0366 | 1.0327 | 2.2139 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7450.098 | 0.9368 | 0.9419 | 2.2139 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7450.098 | 0.8759 | 0.8838 | 2.2139 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7450.098 | 0.8184 | 0.8269 | 2.2139 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7451.091 | 1.0549 | 1.0506 | 2.1415 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7451.091 | 0.9936 | 0.9940 | 2.1415 |