Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7451.091 | 0.9737 | 0.9752 | 2.1415 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7451.091 | 0.9713 | 0.9730 | 2.1415 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7451.091 | 0.9015 | 0.9054 | 2.1415 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7451.091 | 0.7519 | 0.7507 | 2.1415 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7451.091 | 0.7886 | 0.7901 | 2.1415 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7451.091 | 0.0129 | -0.7375 | 2.1415 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 133 | uM | 7451.091 | 0.5066 | 0.4558 | 2.1415 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7452.098 | 1.0269 | 1.0319 | 1.6799 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7452.098 | 0.9918 | 0.9902 | 1.6799 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7452.098 | 1.0619 | 1.0728 | 1.6799 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7452.098 | 1.0290 | 1.0344 | 1.6799 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7452.098 | 0.9657 | 0.9589 | 1.6799 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7452.098 | 0.9961 | 0.9954 | 1.6799 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7452.098 | 0.9485 | 0.9380 | 1.6799 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7452.098 | 0.8177 | 0.7741 | 1.6799 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7452.098 | 0.9472 | 0.9364 | 1.6799 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7453.091 | 0.9820 | 0.9773 | 1.5914 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7453.091 | 1.0420 | 1.0524 | 1.5914 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7453.091 | 0.9775 | 0.9717 | 1.5914 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7453.091 | 0.9265 | 0.9063 | 1.5914 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7453.091 | 0.9430 | 0.9275 | 1.5914 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7453.091 | 0.9462 | 0.9316 | 1.5914 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7453.091 | 0.9968 | 0.9960 | 1.5914 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7453.091 | 0.1296 | -0.4462 | 1.5914 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 133 | uM | 7453.091 | 0.0824 | -0.5833 | 1.5914 |