Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7453.098 | 1.0240 | 1.0326 | 1.4660 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7453.098 | 1.0553 | 1.0748 | 1.4660 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7453.098 | 0.9880 | 0.9836 | 1.4660 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7453.098 | 1.0363 | 1.0493 | 1.4660 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7453.098 | 1.0405 | 1.0549 | 1.4660 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7453.098 | 0.9917 | 0.9886 | 1.4660 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7453.098 | 0.9765 | 0.9678 | 1.4660 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7453.098 | 0.1178 | -0.5351 | 1.4660 | |
| HCC1937 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7453.098 | 0.4832 | 0.2177 | 1.4660 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7454.092 | 0.9021 | 0.8405 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7454.092 | 0.8449 | 0.7460 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7454.092 | 0.8588 | 0.7689 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7454.092 | 0.9415 | 0.9051 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7454.092 | 0.9628 | 0.9398 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7454.092 | 0.8601 | 0.7711 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7454.092 | 0.8514 | 0.7567 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7454.092 | 0.8196 | 0.7036 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7454.092 | 0.8588 | 0.7690 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7454.098 | 0.9964 | 0.9944 | 1.2964 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7454.098 | 0.8488 | 0.7624 | 1.2964 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7454.098 | 0.9847 | 0.9764 | 1.2964 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7454.098 | 0.9424 | 0.9105 | 1.2964 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7454.098 | 0.9869 | 0.9798 | 1.2964 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7454.098 | 0.8809 | 0.8135 | 1.2964 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7454.098 | 0.9712 | 0.9554 | 1.2964 |