Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.00213 | uM | 9759.001 | 0.9494 | 0.9141 | 1.1834 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0107 | uM | 9759.001 | 1.0381 | 1.0643 | 1.1834 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0533 | uM | 9759.001 | 0.1610 | -0.5727 | 1.1834 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.267 | uM | 9759.001 | 0.2035 | -0.4792 | 1.1834 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 1.33 | uM | 9759.001 | 0.3781 | -0.1208 | 1.1834 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 6.67 | uM | 9759.001 | 0.4804 | 0.0763 | 1.1834 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 33.3 | uM | 9759.001 | 0.5222 | 0.1550 | 1.1834 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 9760.001 | 1.0421 | 1.0871 | 0.9677 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.000427 | uM | 9760.001 | 1.0993 | 1.2055 | 0.9677 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.00213 | uM | 9760.001 | 1.0344 | 1.0712 | 0.9677 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0107 | uM | 9760.001 | 1.0413 | 1.0855 | 0.9677 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0533 | uM | 9760.001 | 0.2487 | -0.5252 | 0.9677 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.267 | uM | 9760.001 | 0.2092 | -0.6028 | 0.9677 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 1.33 | uM | 9760.001 | 0.4021 | -0.2199 | 0.9677 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 6.67 | uM | 9760.001 | 0.4760 | -0.0714 | 0.9677 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 33.3 | uM | 9760.001 | 0.0795 | -0.8539 | 0.9677 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 10127.001 | 0.9628 | 0.9133 | 0.8568 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.000427 | uM | 10127.001 | 1.1105 | 1.2603 | 0.8568 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.00213 | uM | 10127.001 | 1.0823 | 1.1935 | 0.8568 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0107 | uM | 10127.001 | 0.9994 | 0.9986 | 0.8568 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0533 | uM | 10127.001 | 0.3492 | -0.4143 | 0.8568 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.267 | uM | 10127.001 | 0.6491 | 0.2078 | 0.8568 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 1.33 | uM | 10127.001 | 0.8053 | 0.5534 | 0.8568 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 6.67 | uM | 10127.001 | 0.7379 | 0.4028 | 0.8568 | |
| SK-BR-3 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 33.3 | uM | 10127.001 | 0.0204 | -0.9787 | 0.8568 |