Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7448.098 | 0.8805 | 0.9138 | 2.8877 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7448.098 | 0.6034 | 0.6790 | 2.8877 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7448.098 | 0.8075 | 0.8573 | 2.8877 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7449.091 | 1.0247 | 1.0271 | 1.8158 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7449.091 | 0.9736 | 0.9707 | 1.8158 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7449.091 | 1.0261 | 1.0286 | 1.8158 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7449.091 | 0.9912 | 0.9903 | 1.8158 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7449.091 | 0.9652 | 0.9614 | 1.8158 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7449.091 | 0.9167 | 0.9064 | 1.8158 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7449.091 | 0.6853 | 0.6242 | 1.8158 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7449.091 | 0.0360 | -0.6792 | 1.8158 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 133 | uM | 7449.091 | 0.0633 | -0.5625 | 1.8158 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7449.098 | 1.0629 | 1.0664 | 1.8675 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7449.098 | 1.0368 | 1.0391 | 1.8675 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7449.098 | 1.0341 | 1.0363 | 1.8675 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7449.098 | 1.0084 | 1.0089 | 1.8675 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7449.098 | 1.0436 | 1.0462 | 1.8675 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7449.098 | 1.0330 | 1.0351 | 1.8675 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7449.098 | 0.9570 | 0.9535 | 1.8675 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7449.098 | 0.4062 | 0.2346 | 1.8675 | |
| HCC1569 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7449.098 | 0.3548 | 0.1483 | 1.8675 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7450.071 | 0.9932 | 0.9942 | 2.3612 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7450.071 | 1.0245 | 1.0206 | 2.3612 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7450.071 | 1.0697 | 1.0579 | 2.3612 | |
| HCC1806 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7450.071 | 1.0335 | 1.0281 | 2.3612 |