Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7467.098 | 0.9765 | 0.9668 | 1.4178 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7467.098 | 1.0164 | 1.0231 | 1.4178 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7467.098 | 0.9501 | 0.9291 | 1.4178 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7467.098 | 0.9973 | 0.9962 | 1.4178 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7467.098 | 0.9392 | 0.9135 | 1.4178 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7467.098 | 0.9936 | 0.9910 | 1.4178 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7467.098 | 0.8675 | 0.8093 | 1.4178 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7467.098 | 0.3715 | -0.0052 | 1.4178 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7467.098 | 0.3082 | -0.1281 | 1.4178 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7468.091 | 0.9790 | 0.9717 | 1.4852 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7468.091 | 0.9720 | 0.9621 | 1.4852 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7468.091 | 0.9782 | 0.9706 | 1.4852 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7468.091 | 1.0172 | 1.0231 | 1.4852 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7468.091 | 1.0174 | 1.0234 | 1.4852 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7468.091 | 0.8965 | 0.8581 | 1.4852 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7468.091 | 0.9012 | 0.8648 | 1.4852 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7468.091 | 0.0104 | -0.9077 | 1.4852 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 133 | uM | 7468.091 | 0.0081 | -0.9216 | 1.4852 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7469.071 | 1.0736 | 1.0664 | 2.1768 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7469.071 | 1.0761 | 1.0685 | 2.1768 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7469.071 | 0.9636 | 0.9663 | 2.1768 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7469.071 | 0.9588 | 0.9617 | 2.1768 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7469.071 | 0.9197 | 0.9246 | 2.1768 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7469.071 | 0.8909 | 0.8966 | 2.1768 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7469.071 | 0.9320 | 0.9364 | 2.1768 |