Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 10002.001 | 0.9299 | 0.7468 | 0.5372 | |
| 184A1 | NM | Basal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 10002.001 | 0.1368 | -0.9507 | 0.5372 | |
| 184B5 | NM | Basal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 9095.001 | 1.0160 | 1.0306 | 1.0444 | |
| 184B5 | NM | Basal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 9095.001 | 1.0192 | 1.0368 | 1.0444 | |
| 184B5 | NM | Basal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 9095.001 | 1.0241 | 1.0461 | 1.0444 | |
| 184B5 | NM | Basal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 9095.001 | 0.9572 | 0.9180 | 1.0444 | |
| 184B5 | NM | Basal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 9095.001 | 0.7888 | 0.5935 | 1.0444 | |
| 184B5 | NM | Basal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 9095.001 | 0.7907 | 0.5972 | 1.0444 | |
| 184B5 | NM | Basal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 9095.001 | 0.7562 | 0.5305 | 1.0444 | |
| 184B5 | NM | Basal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 9095.001 | 0.8050 | 0.6248 | 1.0444 | |
| 184B5 | NM | Basal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 9095.001 | 0.1430 | -0.6893 | 1.0444 | |
| 600MPE | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 9118.001 | 1.0665 | 1.1211 | 1.0946 | |
| 600MPE | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 9118.001 | 1.0145 | 1.0264 | 1.0946 | |
| 600MPE | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 9118.001 | 1.0464 | 1.0846 | 1.0946 | |
| 600MPE | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 9118.001 | 0.9872 | 0.9766 | 1.0946 | |
| 600MPE | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 9118.001 | 0.9364 | 0.8835 | 1.0946 | |
| 600MPE | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 9118.001 | 0.7180 | 0.4777 | 1.0946 | |
| 600MPE | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 9118.001 | 0.9166 | 0.8471 | 1.0946 | |
| 600MPE | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 9118.001 | 0.9991 | 0.9983 | 1.0946 | |
| 600MPE | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 9118.001 | 0.7811 | 0.5960 | 1.0946 | |
| 600MPE | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 9120.001 | 1.0061 | 1.0197 | 0.6180 | |
| 600MPE | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 9120.001 | 0.9788 | 0.9319 | 0.6180 | |
| 600MPE | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 9120.001 | 1.0170 | 1.0553 | 0.6180 | |
| 600MPE | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 9120.001 | 0.9745 | 0.9182 | 0.6180 | |
| 600MPE | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 9120.001 | 0.9502 | 0.8412 | 0.6180 |