Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
ZR75B	HR+	Luminal	GSK461364	PLK1	PLK	0.0000853	uM	9997.001	1.0831	1.1661	1.0003
ZR75B	HR+	Luminal	GSK461364	PLK1	PLK	0.000427	uM	9997.001	1.0283	1.0566	1.0003
ZR75B	HR+	Luminal	GSK461364	PLK1	PLK	0.00213	uM	9997.001	1.0333	1.0666	1.0003
ZR75B	HR+	Luminal	GSK461364	PLK1	PLK	0.0107	uM	9997.001	0.9655	0.9310	1.0003
ZR75B	HR+	Luminal	GSK461364	PLK1	PLK	0.0533	uM	9997.001	0.7794	0.5590	1.0003
ZR75B	HR+	Luminal	GSK461364	PLK1	PLK	0.267	uM	9997.001	0.5198	0.0399	1.0003
ZR75B	HR+	Luminal	GSK461364	PLK1	PLK	1.33	uM	9997.001	0.5559	0.1120	1.0003
ZR75B	HR+	Luminal	GSK461364	PLK1	PLK	6.67	uM	9997.001	0.5838	0.1677	1.0003
ZR75B	HR+	Luminal	GSK461364	PLK1	PLK	33.3	uM	9997.001	0.1515	-0.6969	1.0003
184A1	NM	Basal	GSK923295	CENPE	Kinesin	0.0000853	uM	9047.001	0.9657	0.9114	0.7701
184A1	NM	Basal	GSK923295	CENPE	Kinesin	0.000427	uM	9047.001	0.8741	0.6793	0.7701
184A1	NM	Basal	GSK923295	CENPE	Kinesin	0.00213	uM	9047.001	0.9420	0.8506	0.7701
184A1	NM	Basal	GSK923295	CENPE	Kinesin	0.0107	uM	9047.001	0.9499	0.8709	0.7701
184A1	NM	Basal	GSK923295	CENPE	Kinesin	0.0533	uM	9047.001	0.9131	0.7774	0.7701
184A1	NM	Basal	GSK923295	CENPE	Kinesin	0.267	uM	9047.001	0.9128	0.7765	0.7701
184A1	NM	Basal	GSK923295	CENPE	Kinesin	1.33	uM	9047.001	0.9103	0.7701	0.7701
184A1	NM	Basal	GSK923295	CENPE	Kinesin	6.67	uM	9047.001	0.9189	0.7920	0.7701
184A1	NM	Basal	GSK923295	CENPE	Kinesin	33.3	uM	9047.001	0.6037	0.0385	0.7701
184A1	NM	Basal	GSK923295	CENPE	Kinesin	0.0000853	uM	10002.001	0.9750	0.9077	0.5372
184A1	NM	Basal	GSK923295	CENPE	Kinesin	0.000427	uM	10002.001	0.9847	0.9434	0.5372
184A1	NM	Basal	GSK923295	CENPE	Kinesin	0.00213	uM	10002.001	1.0385	1.1456	0.5372
184A1	NM	Basal	GSK923295	CENPE	Kinesin	0.0107	uM	10002.001	0.9386	0.7776	0.5372
184A1	NM	Basal	GSK923295	CENPE	Kinesin	0.0533	uM	10002.001	0.9861	0.9486	0.5372
184A1	NM	Basal	GSK923295	CENPE	Kinesin	0.267	uM	10002.001	0.9098	0.6773	0.5372
184A1	NM	Basal	GSK923295	CENPE	Kinesin	1.33	uM	10002.001	0.9869	0.9514	0.5372

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)