Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | ICRF-193 | TOP2 | TOP | 6.67 | uM | 10577.139 | 0.8996 | 0.7835 | 0.9234 | |
| HCC3153 | TNBC | Basal A | ICRF-193 | TOP2 | TOP | 33.3 | uM | 10577.139 | 1.0014 | 1.0031 | 0.9234 | |
| HCC3153 | TNBC | Basal A | ICRF-193 | TOP2 | TOP | 0.0000853 | uM | 10937.151 | 0.9588 | 0.9455 | 1.5219 | |
| HCC3153 | TNBC | Basal A | ICRF-193 | TOP2 | TOP | 0.000427 | uM | 10937.151 | 1.0413 | 1.0539 | 1.5219 | |
| HCC3153 | TNBC | Basal A | ICRF-193 | TOP2 | TOP | 0.00213 | uM | 10937.151 | 0.9654 | 0.9542 | 1.5219 | |
| HCC3153 | TNBC | Basal A | ICRF-193 | TOP2 | TOP | 0.0107 | uM | 10937.151 | 0.9318 | 0.9093 | 1.5219 | |
| HCC3153 | TNBC | Basal A | ICRF-193 | TOP2 | TOP | 0.0533 | uM | 10937.151 | 0.9953 | 0.9938 | 1.5219 | |
| HCC3153 | TNBC | Basal A | ICRF-193 | TOP2 | TOP | 0.267 | uM | 10937.151 | 0.8210 | 0.7569 | 1.5219 | |
| HCC3153 | TNBC | Basal A | ICRF-193 | TOP2 | TOP | 1.33 | uM | 10937.151 | 0.7653 | 0.6776 | 1.5219 | |
| HCC3153 | TNBC | Basal A | ICRF-193 | TOP2 | TOP | 6.67 | uM | 10937.151 | 0.7424 | 0.6444 | 1.5219 | |
| HCC3153 | TNBC | Basal A | ICRF-193 | TOP2 | TOP | 33.3 | uM | 10937.151 | 0.8042 | 0.7332 | 1.5219 | |
| HCC38 | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.0000853 | uM | 10578.139 | 0.9445 | 0.9317 | 1.6434 | |
| HCC38 | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.000427 | uM | 10578.139 | 0.9518 | 0.9408 | 1.6434 | |
| HCC38 | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.00213 | uM | 10578.139 | 0.8939 | 0.8680 | 1.6434 | |
| HCC38 | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.0107 | uM | 10578.139 | 1.0085 | 1.0104 | 1.6434 | |
| HCC38 | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.0533 | uM | 10578.139 | 1.0292 | 1.0353 | 1.6434 | |
| HCC38 | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.267 | uM | 10578.139 | 0.7968 | 0.7419 | 1.6434 | |
| HCC38 | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 1.33 | uM | 10578.139 | 0.5154 | 0.3362 | 1.6434 | |
| HCC38 | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 6.67 | uM | 10578.139 | 0.3764 | 0.1037 | 1.6434 | |
| HCC38 | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 33.3 | uM | 10578.139 | 0.7083 | 0.6214 | 1.6434 | |
| HCC38 | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.000128 | uM | 11850.157 | 0.8840 | 0.8856 | 2.0943 | |
| HCC38 | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.00064 | uM | 11850.157 | 0.9236 | 0.9255 | 2.0943 | |
| HCC38 | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.0032 | uM | 11850.157 | 0.9135 | 0.9155 | 2.0943 | |
| HCC38 | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.016 | uM | 11850.157 | 0.8874 | 0.8891 | 2.0943 | |
| HCC38 | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.08 | uM | 11850.157 | 0.8662 | 0.8674 | 2.0943 |