Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7465.092 | 0.9799 | 0.9665 | 1.2055 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7465.092 | 0.8012 | 0.6640 | 1.2055 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7465.092 | 0.6570 | 0.4115 | 1.2055 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7465.092 | 0.7524 | 0.5796 | 1.2055 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7465.092 | 0.6143 | 0.3351 | 1.2055 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7465.098 | 0.9937 | 0.9897 | 1.2188 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7465.098 | 0.9224 | 0.8717 | 1.2188 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7465.098 | 0.9808 | 0.9685 | 1.2188 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7465.098 | 0.9504 | 0.9182 | 1.2188 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7465.098 | 0.8982 | 0.8314 | 1.2188 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7465.098 | 0.8533 | 0.7559 | 1.2188 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7465.098 | 0.6864 | 0.4688 | 1.2188 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7465.098 | 0.5638 | 0.2498 | 1.2188 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7465.098 | 0.2148 | -0.4338 | 1.2188 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7466.092 | 1.0506 | 1.1108 | 0.9158 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7466.092 | 0.9633 | 0.9201 | 0.9158 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7466.092 | 1.0119 | 1.0261 | 0.9158 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7466.092 | 1.0008 | 1.0018 | 0.9158 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7466.092 | 0.9957 | 0.9907 | 0.9158 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7466.092 | 0.9229 | 0.8323 | 0.9158 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7466.092 | 0.8584 | 0.6929 | 0.9158 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7466.092 | 0.7968 | 0.5606 | 0.9158 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7466.092 | 0.2827 | -0.4966 | 0.9158 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7466.098 | 0.9929 | 0.9828 | 0.8226 | |
| HCC3153 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7466.098 | 0.9905 | 0.9770 | 0.8226 |