Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7440.098 | 1.0314 | 1.1790 | 0.3606 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7440.098 | 0.9878 | 0.9331 | 0.3606 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7440.098 | 0.8982 | 0.4852 | 0.3606 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7440.098 | 0.0359 | -0.9998 | 0.3606 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7441.09 | 1.0094 | 1.0257 | 0.7331 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7441.09 | 1.0369 | 1.1015 | 0.7331 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7441.09 | 1.0139 | 1.0381 | 0.7331 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7441.09 | 1.0725 | 1.2003 | 0.7331 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7441.09 | 0.9882 | 0.9679 | 0.7331 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7441.09 | 0.8893 | 0.7042 | 0.7331 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7441.09 | 0.3165 | -0.5836 | 0.7331 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7441.09 | 0.3816 | -0.4627 | 0.7331 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7441.09 | 0.7077 | 0.2480 | 0.7331 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7442.092 | 1.0250 | 1.0642 | 0.7831 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7442.092 | 0.9733 | 0.9320 | 0.7831 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7442.092 | 0.9762 | 0.9395 | 0.7831 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7442.092 | 0.9713 | 0.9269 | 0.7831 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7442.092 | 0.9728 | 0.9308 | 0.7831 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7442.092 | 0.8894 | 0.7219 | 0.7831 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7442.092 | 0.6843 | 0.2320 | 0.7831 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7442.092 | 0.0185 | -0.9877 | 0.7831 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7442.092 | 0.4543 | -0.2697 | 0.7831 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7442.098 | 1.0284 | 1.0657 | 0.8652 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7442.098 | 1.0124 | 1.0287 | 0.8652 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7442.098 | 1.0202 | 1.0467 | 0.8652 |