Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7436.091 | 0.0205 | -0.9110 | 1.2489 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 133 | uM | 7436.091 | 0.8544 | 0.7631 | 1.2489 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7437.091 | 1.0154 | 1.0914 | 0.3419 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7437.091 | 1.0388 | 1.2357 | 0.3419 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7437.091 | 1.0195 | 1.1160 | 0.3419 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7437.091 | 1.0182 | 1.1083 | 0.3419 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7437.091 | 0.9705 | 0.8324 | 0.3419 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7437.091 | 0.9950 | 0.9711 | 0.3419 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7437.091 | 0.9939 | 0.9646 | 0.3419 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7437.091 | 0.6442 | -0.4472 | 0.3419 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7437.091 | 0.0950 | -0.9980 | 0.3419 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7440.091 | 1.0426 | 1.2061 | 0.4250 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7440.091 | 0.9810 | 0.9117 | 0.4250 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7440.091 | 0.9394 | 0.7265 | 0.4250 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7440.091 | 0.9896 | 0.9516 | 0.4250 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7440.091 | 0.9644 | 0.8365 | 0.4250 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7440.091 | 0.9682 | 0.8537 | 0.4250 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7440.091 | 0.8975 | 0.5508 | 0.4250 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7440.091 | 0.5400 | -0.5307 | 0.4250 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7440.091 | 0.4804 | -0.6436 | 0.4250 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7440.098 | 0.9774 | 0.8771 | 0.3606 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7440.098 | 0.9941 | 0.9673 | 0.3606 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7440.098 | 0.9741 | 0.8596 | 0.3606 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7440.098 | 0.9924 | 0.9581 | 0.3606 | |
| HCC1419 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7440.098 | 1.0130 | 1.0729 | 0.3606 |