Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7435.091 | 0.9868 | 0.9542 | 0.5716 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7435.091 | 0.9627 | 0.8714 | 0.5716 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7435.091 | 1.0476 | 1.1696 | 0.5716 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7435.091 | 1.0028 | 1.0099 | 0.5716 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7435.091 | 1.0142 | 1.0499 | 0.5716 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7435.091 | 0.9295 | 0.7598 | 0.5716 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7435.091 | 0.7453 | 0.1959 | 0.5716 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7435.091 | 0.0006 | -1.0000 | 0.5716 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 133 | uM | 7435.091 | 0.0006 | -1.0000 | 0.5716 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7435.098 | 0.9553 | 0.8848 | 0.7702 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7435.098 | 0.9474 | 0.8645 | 0.7702 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7435.098 | 0.9610 | 0.8993 | 0.7702 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7435.098 | 0.9744 | 0.9338 | 0.7702 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7435.098 | 0.9472 | 0.8640 | 0.7702 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7435.098 | 0.9460 | 0.8609 | 0.7702 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7435.098 | 0.9010 | 0.7467 | 0.7702 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7435.098 | 0.3461 | -0.4957 | 0.7702 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7435.098 | 0.8067 | 0.5132 | 0.7702 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7436.091 | 1.0642 | 1.1021 | 1.2489 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7436.091 | 0.9869 | 0.9790 | 1.2489 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7436.091 | 0.9834 | 0.9734 | 1.2489 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7436.091 | 1.0216 | 1.0346 | 1.2489 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7436.091 | 1.0224 | 1.0357 | 1.2489 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7436.091 | 0.9289 | 0.8853 | 1.2489 | |
| HCC1395 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7436.091 | 0.9342 | 0.8939 | 1.2489 |