Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7442.098 | 0.9804 | 0.9547 | 0.8652 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7442.098 | 0.9830 | 0.9608 | 0.8652 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7442.098 | 0.9078 | 0.7884 | 0.8652 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7442.098 | 0.9053 | 0.7827 | 0.8652 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7442.098 | 0.0619 | -0.9197 | 0.8652 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7442.098 | 0.6965 | 0.3166 | 0.8652 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7443.07 | 0.9914 | 0.9818 | 0.9389 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7443.07 | 0.9785 | 0.9542 | 0.9389 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7443.07 | 1.0000 | 1.0000 | 0.9389 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7443.07 | 1.0015 | 1.0033 | 0.9389 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7443.07 | 0.9000 | 0.7877 | 0.9389 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7443.07 | 0.8776 | 0.7404 | 0.9389 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7443.07 | 0.6520 | 0.2682 | 0.9389 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7443.07 | 0.0416 | -0.9324 | 0.9389 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7443.07 | 0.0199 | -0.9691 | 0.9389 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7443.09 | 1.0144 | 1.0305 | 0.9451 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7443.09 | 1.0487 | 1.1031 | 0.9451 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7443.09 | 0.9938 | 0.9869 | 0.9451 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7443.09 | 1.0167 | 1.0353 | 0.9451 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7443.09 | 0.9350 | 0.8627 | 0.9451 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7443.09 | 0.8780 | 0.7427 | 0.9451 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7443.09 | 0.3896 | -0.2623 | 0.9451 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7443.09 | 0.6743 | 0.3181 | 0.9451 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7443.09 | 0.3954 | -0.2507 | 0.9451 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7443.098 | 0.9737 | 0.9428 | 0.9189 |