Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7443.098 | 1.0005 | 1.0012 | 0.9189 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7443.098 | 0.9626 | 0.9187 | 0.9189 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7443.098 | 0.9903 | 0.9789 | 0.9189 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7443.098 | 0.9461 | 0.8829 | 0.9189 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7443.098 | 0.8682 | 0.7148 | 0.9189 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7443.098 | 0.6782 | 0.3107 | 0.9189 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7443.098 | 0.0462 | -0.9295 | 0.9189 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7443.098 | 0.0201 | -0.9715 | 0.9189 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7444.071 | 0.9900 | 0.9754 | 0.8133 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7444.071 | 1.0445 | 1.1099 | 0.8133 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7444.071 | 1.0084 | 1.0206 | 0.8133 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7444.071 | 1.0027 | 1.0065 | 0.8133 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7444.071 | 0.9522 | 0.8832 | 0.8133 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7444.071 | 0.8592 | 0.6595 | 0.8133 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7444.071 | 0.6731 | 0.2293 | 0.8133 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 24 | uM | 7444.071 | 0.0245 | -0.9791 | 0.8133 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 120 | uM | 7444.071 | 0.0234 | -0.9802 | 0.8133 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7444.091 | 1.0526 | 1.1206 | 0.8764 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7444.091 | 0.9907 | 0.9788 | 0.8764 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7444.091 | 0.9772 | 0.9481 | 0.8764 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7444.091 | 0.9818 | 0.9586 | 0.8764 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7444.091 | 0.9196 | 0.8175 | 0.8764 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7444.091 | 0.7509 | 0.4424 | 0.8764 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7444.091 | 0.5218 | -0.0479 | 0.8764 | |
| HCC1428 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7444.091 | 0.4413 | -0.2137 | 0.8764 |