Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5911.07 | 0.9666 | 0.9376 | 1.0709 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5911.07 | 0.9208 | 0.8518 | 1.0709 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5911.07 | 0.9478 | 0.9023 | 1.0709 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5911.07 | 0.9374 | 0.8828 | 1.0709 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5911.07 | 0.0631 | -0.8485 | 1.0709 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5911.07 | 0.0448 | -0.8899 | 1.0709 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 5911.09 | 0.9827 | 0.9687 | 1.1067 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 5911.09 | 0.9610 | 0.9293 | 1.1067 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 5911.09 | 1.0290 | 1.0524 | 1.1067 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 5911.09 | 0.9425 | 0.8958 | 1.1067 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 5911.09 | 0.9371 | 0.8861 | 1.1067 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 5911.09 | 0.9917 | 0.9849 | 1.1067 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 5911.09 | 0.8872 | 0.7950 | 1.1067 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 5911.09 | 0.9239 | 0.8619 | 1.1067 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 5911.09 | 0.8448 | 0.7173 | 1.1067 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5911.098 | 0.9715 | 0.9464 | 1.0659 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5911.098 | 0.9891 | 0.9795 | 1.0659 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5911.098 | 0.9652 | 0.9346 | 1.0659 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5911.098 | 1.0136 | 1.0255 | 1.0659 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5911.098 | 0.9662 | 0.9366 | 1.0659 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5911.098 | 0.9942 | 0.9892 | 1.0659 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5911.098 | 0.9550 | 0.9155 | 1.0659 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5911.098 | 0.0595 | -0.8584 | 1.0659 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5911.098 | 0.0541 | -0.8704 | 1.0659 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 5912.071 | 0.9558 | 0.9272 | 1.2176 |