Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5908.098 | 0.0523 | -0.9842 | 0.6091 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5908.098 | 0.8272 | 0.4646 | 0.6091 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5909.092 | 1.0224 | 1.0147 | 3.0314 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5909.092 | 1.0125 | 1.0082 | 3.0314 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5909.092 | 0.9488 | 0.9656 | 3.0314 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5909.092 | 1.0370 | 1.0241 | 3.0314 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5909.092 | 1.0256 | 1.0168 | 3.0314 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5909.092 | 0.9328 | 0.9546 | 3.0314 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5909.092 | 0.9282 | 0.9514 | 3.0314 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5909.092 | 0.0055 | -0.6407 | 3.0314 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5909.092 | 0.0027 | -0.7169 | 3.0314 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5909.098 | 1.0595 | 1.0445 | 2.6253 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5909.098 | 1.0359 | 1.0271 | 2.6253 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5909.098 | 1.0631 | 1.0471 | 2.6253 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5909.098 | 1.0761 | 1.0567 | 2.6253 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5909.098 | 1.0378 | 1.0284 | 2.6253 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5909.098 | 1.0438 | 1.0330 | 2.6253 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5909.098 | 1.0410 | 1.0309 | 2.6253 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5909.098 | 0.0040 | -0.7568 | 2.6253 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5909.098 | 0.0004 | -0.8961 | 2.6253 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5910.07 | 1.0070 | 1.0042 | 3.3174 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5910.07 | 1.0341 | 1.0203 | 3.3174 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5910.07 | 0.9205 | 0.9507 | 3.3174 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5910.07 | 1.0043 | 1.0026 | 3.3174 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5910.07 | 0.9661 | 0.9793 | 3.3174 |