Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | GM6001 | MMP | MMP | 6.67 | uM | 7430.096 | 0.8532 | 0.8486 | 2.0162 | |
| HCC1143 | TNBC | Basal A | GM6001 | MMP | MMP | 33.3 | uM | 7430.096 | 0.8302 | 0.8237 | 2.0162 | |
| HCC1395 | TNBC | Basal B | GM6001 | MMP | MMP | 0.0000853 | uM | 7436.096 | 0.9074 | 0.8657 | 1.3979 | |
| HCC1395 | TNBC | Basal B | GM6001 | MMP | MMP | 0.000427 | uM | 7436.096 | 0.9480 | 0.9250 | 1.3979 | |
| HCC1395 | TNBC | Basal B | GM6001 | MMP | MMP | 0.00213 | uM | 7436.096 | 0.8911 | 0.8417 | 1.3979 | |
| HCC1395 | TNBC | Basal B | GM6001 | MMP | MMP | 0.0107 | uM | 7436.096 | 1.0189 | 1.0270 | 1.3979 | |
| HCC1395 | TNBC | Basal B | GM6001 | MMP | MMP | 0.0533 | uM | 7436.096 | 0.9754 | 0.9647 | 1.3979 | |
| HCC1395 | TNBC | Basal B | GM6001 | MMP | MMP | 0.267 | uM | 7436.096 | 0.9777 | 0.9680 | 1.3979 | |
| HCC1395 | TNBC | Basal B | GM6001 | MMP | MMP | 1.33 | uM | 7436.096 | 0.9788 | 0.9696 | 1.3979 | |
| HCC1395 | TNBC | Basal B | GM6001 | MMP | MMP | 6.67 | uM | 7436.096 | 0.9111 | 0.8711 | 1.3979 | |
| HCC1395 | TNBC | Basal B | GM6001 | MMP | MMP | 33.3 | uM | 7436.096 | 0.8823 | 0.8287 | 1.3979 | |
| HCC1428 | HR+ | Luminal | GM6001 | MMP | MMP | 0.0000853 | uM | 7442.096 | 0.9776 | 0.9418 | 0.7665 | |
| HCC1428 | HR+ | Luminal | GM6001 | MMP | MMP | 0.000427 | uM | 7442.096 | 0.9912 | 0.9771 | 0.7665 | |
| HCC1428 | HR+ | Luminal | GM6001 | MMP | MMP | 0.00213 | uM | 7442.096 | 0.9741 | 0.9326 | 0.7665 | |
| HCC1428 | HR+ | Luminal | GM6001 | MMP | MMP | 0.0107 | uM | 7442.096 | 0.9921 | 0.9795 | 0.7665 | |
| HCC1428 | HR+ | Luminal | GM6001 | MMP | MMP | 0.0533 | uM | 7442.096 | 1.0139 | 1.0363 | 0.7665 | |
| HCC1428 | HR+ | Luminal | GM6001 | MMP | MMP | 0.267 | uM | 7442.096 | 0.9458 | 0.8598 | 0.7665 | |
| HCC1428 | HR+ | Luminal | GM6001 | MMP | MMP | 1.33 | uM | 7442.096 | 0.9850 | 0.9611 | 0.7665 | |
| HCC1428 | HR+ | Luminal | GM6001 | MMP | MMP | 6.67 | uM | 7442.096 | 0.9553 | 0.8841 | 0.7665 | |
| HCC1428 | HR+ | Luminal | GM6001 | MMP | MMP | 33.3 | uM | 7442.096 | 0.9374 | 0.8382 | 0.7665 | |
| HCC1806 | TNBC | Basal A | GM6001 | MMP | MMP | 0.0000853 | uM | 7451.096 | 0.9426 | 0.9466 | 2.1851 | |
| HCC1806 | TNBC | Basal A | GM6001 | MMP | MMP | 0.000427 | uM | 7451.096 | 0.9576 | 0.9607 | 2.1851 | |
| HCC1806 | TNBC | Basal A | GM6001 | MMP | MMP | 0.00213 | uM | 7451.096 | 0.9358 | 0.9401 | 2.1851 | |
| HCC1806 | TNBC | Basal A | GM6001 | MMP | MMP | 0.0107 | uM | 7451.096 | 0.9594 | 0.9624 | 2.1851 | |
| HCC1806 | TNBC | Basal A | GM6001 | MMP | MMP | 0.0533 | uM | 7451.096 | 0.9738 | 0.9758 | 2.1851 |