Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | GM6001 | MMP | MMP | 0.267 | uM | 7451.096 | 0.9491 | 0.9528 | 2.1851 | |
| HCC1806 | TNBC | Basal A | GM6001 | MMP | MMP | 1.33 | uM | 7451.096 | 0.8897 | 0.8958 | 2.1851 | |
| HCC1806 | TNBC | Basal A | GM6001 | MMP | MMP | 6.67 | uM | 7451.096 | 0.8459 | 0.8525 | 2.1851 | |
| HCC1806 | TNBC | Basal A | GM6001 | MMP | MMP | 33.3 | uM | 7451.096 | 0.7904 | 0.7959 | 2.1851 | |
| HCC2185 | TNBC | Luminal | GM6001 | MMP | MMP | 0.0000853 | uM | 7462.096 | 0.9763 | 0.8680 | 0.3514 | |
| HCC2185 | TNBC | Luminal | GM6001 | MMP | MMP | 0.000427 | uM | 7462.096 | 0.9791 | 0.8834 | 0.3514 | |
| HCC2185 | TNBC | Luminal | GM6001 | MMP | MMP | 0.00213 | uM | 7462.096 | 0.9883 | 0.9342 | 0.3514 | |
| HCC2185 | TNBC | Luminal | GM6001 | MMP | MMP | 0.0107 | uM | 7462.096 | 1.0189 | 1.1096 | 0.3514 | |
| HCC2185 | TNBC | Luminal | GM6001 | MMP | MMP | 0.0533 | uM | 7462.096 | 1.0205 | 1.1189 | 0.3514 | |
| HCC2185 | TNBC | Luminal | GM6001 | MMP | MMP | 0.267 | uM | 7462.096 | 0.9796 | 0.8863 | 0.3514 | |
| HCC2185 | TNBC | Luminal | GM6001 | MMP | MMP | 1.33 | uM | 7462.096 | 0.9736 | 0.8533 | 0.3514 | |
| HCC2185 | TNBC | Luminal | GM6001 | MMP | MMP | 6.67 | uM | 7462.096 | 0.9137 | 0.5469 | 0.3514 | |
| HCC2185 | TNBC | Luminal | GM6001 | MMP | MMP | 33.3 | uM | 7462.096 | 0.9094 | 0.5261 | 0.3514 | |
| HCC3153 | TNBC | Basal A | GM6001 | MMP | MMP | 0.0000853 | uM | 7466.096 | 0.9307 | 0.8508 | 0.9269 | |
| HCC3153 | TNBC | Basal A | GM6001 | MMP | MMP | 0.000427 | uM | 7466.096 | 0.9701 | 0.9357 | 0.9269 | |
| HCC3153 | TNBC | Basal A | GM6001 | MMP | MMP | 0.00213 | uM | 7466.096 | 0.9377 | 0.8659 | 0.9269 | |
| HCC3153 | TNBC | Basal A | GM6001 | MMP | MMP | 0.0107 | uM | 7466.096 | 0.9786 | 0.9539 | 0.9269 | |
| HCC3153 | TNBC | Basal A | GM6001 | MMP | MMP | 0.0533 | uM | 7466.096 | 0.9863 | 0.9705 | 0.9269 | |
| HCC3153 | TNBC | Basal A | GM6001 | MMP | MMP | 0.267 | uM | 7466.096 | 0.9702 | 0.9358 | 0.9269 | |
| HCC3153 | TNBC | Basal A | GM6001 | MMP | MMP | 1.33 | uM | 7466.096 | 0.9337 | 0.8574 | 0.9269 | |
| HCC3153 | TNBC | Basal A | GM6001 | MMP | MMP | 6.67 | uM | 7466.096 | 0.9520 | 0.8967 | 0.9269 | |
| HCC3153 | TNBC | Basal A | GM6001 | MMP | MMP | 33.3 | uM | 7466.096 | 0.9975 | 0.9945 | 0.9269 | |
| HCC38 | TNBC | Basal B | GM6001 | MMP | MMP | 0.0000853 | uM | 7468.096 | 0.9234 | 0.9009 | 1.5683 | |
| HCC38 | TNBC | Basal B | GM6001 | MMP | MMP | 0.000427 | uM | 7468.096 | 0.9766 | 0.9700 | 1.5683 | |
| HCC38 | TNBC | Basal B | GM6001 | MMP | MMP | 0.00213 | uM | 7468.096 | 0.9423 | 0.9257 | 1.5683 |