Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | GM6001 | MMP | MMP | 0.0000853 | uM | 5905.096 | 0.7904 | 0.5439 | 0.9091 | |
| BT-474 | HER2amp | Luminal | GM6001 | MMP | MMP | 0.000427 | uM | 5905.096 | 1.0268 | 1.0590 | 0.9091 | |
| BT-474 | HER2amp | Luminal | GM6001 | MMP | MMP | 0.00213 | uM | 5905.096 | 0.9496 | 0.8893 | 0.9091 | |
| BT-474 | HER2amp | Luminal | GM6001 | MMP | MMP | 0.0107 | uM | 5905.096 | 0.9950 | 0.9891 | 0.9091 | |
| BT-474 | HER2amp | Luminal | GM6001 | MMP | MMP | 0.0533 | uM | 5905.096 | 1.1543 | 1.3421 | 0.9091 | |
| BT-474 | HER2amp | Luminal | GM6001 | MMP | MMP | 0.267 | uM | 5905.096 | 0.9891 | 0.9760 | 0.9091 | |
| BT-474 | HER2amp | Luminal | GM6001 | MMP | MMP | 1.33 | uM | 5905.096 | 1.0566 | 1.1249 | 0.9091 | |
| BT-474 | HER2amp | Luminal | GM6001 | MMP | MMP | 6.67 | uM | 5905.096 | 0.7221 | 0.3979 | 0.9091 | |
| BT-474 | HER2amp | Luminal | GM6001 | MMP | MMP | 33.3 | uM | 5905.096 | 0.9539 | 0.8989 | 0.9091 | |
| BT-549 | TNBC | Basal B | GM6001 | MMP | MMP | 0.0000853 | uM | 5909.096 | 0.9794 | 0.9863 | 3.0117 | |
| BT-549 | TNBC | Basal B | GM6001 | MMP | MMP | 0.000427 | uM | 5909.096 | 0.9794 | 0.9863 | 3.0117 | |
| BT-549 | TNBC | Basal B | GM6001 | MMP | MMP | 0.00213 | uM | 5909.096 | 0.9337 | 0.9549 | 3.0117 | |
| BT-549 | TNBC | Basal B | GM6001 | MMP | MMP | 0.0107 | uM | 5909.096 | 1.0233 | 1.0153 | 3.0117 | |
| BT-549 | TNBC | Basal B | GM6001 | MMP | MMP | 0.0533 | uM | 5909.096 | 1.0387 | 1.0254 | 3.0117 | |
| BT-549 | TNBC | Basal B | GM6001 | MMP | MMP | 0.267 | uM | 5909.096 | 0.9700 | 0.9799 | 3.0117 | |
| BT-549 | TNBC | Basal B | GM6001 | MMP | MMP | 1.33 | uM | 5909.096 | 0.9398 | 0.9592 | 3.0117 | |
| BT-549 | TNBC | Basal B | GM6001 | MMP | MMP | 6.67 | uM | 5909.096 | 0.9106 | 0.9388 | 3.0117 | |
| BT-549 | TNBC | Basal B | GM6001 | MMP | MMP | 33.3 | uM | 5909.096 | 0.8522 | 0.8966 | 3.0117 | |
| HCC1143 | TNBC | Basal A | GM6001 | MMP | MMP | 0.0000853 | uM | 7430.096 | 0.9352 | 0.9346 | 2.0162 | |
| HCC1143 | TNBC | Basal A | GM6001 | MMP | MMP | 0.000427 | uM | 7430.096 | 0.9248 | 0.9239 | 2.0162 | |
| HCC1143 | TNBC | Basal A | GM6001 | MMP | MMP | 0.00213 | uM | 7430.096 | 0.9419 | 0.9415 | 2.0162 | |
| HCC1143 | TNBC | Basal A | GM6001 | MMP | MMP | 0.0107 | uM | 7430.096 | 0.9503 | 0.9501 | 2.0162 | |
| HCC1143 | TNBC | Basal A | GM6001 | MMP | MMP | 0.0533 | uM | 7430.096 | 0.9627 | 0.9626 | 2.0162 | |
| HCC1143 | TNBC | Basal A | GM6001 | MMP | MMP | 0.267 | uM | 7430.096 | 0.9137 | 0.9124 | 2.0162 | |
| HCC1143 | TNBC | Basal A | GM6001 | MMP | MMP | 1.33 | uM | 7430.096 | 0.9239 | 0.9230 | 2.0162 |