Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 24 | uM | 7483.071 | 0.1762 | 0.2279 | 3.5590 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 120 | uM | 7483.071 | 0.3470 | 0.4854 | 3.5590 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7483.091 | 1.0102 | 1.0067 | 3.0465 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7483.091 | 1.0579 | 1.0373 | 3.0465 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7483.091 | 0.9461 | 0.9639 | 3.0465 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7483.091 | 1.0096 | 1.0063 | 3.0465 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7483.091 | 0.9488 | 0.9658 | 3.0465 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7483.091 | 0.7712 | 0.8365 | 3.0465 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7483.091 | 0.5390 | 0.6328 | 3.0465 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7483.091 | 0.0175 | -0.4695 | 3.0465 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 133 | uM | 7483.091 | 0.0992 | -0.0633 | 3.0465 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7483.098 | 0.9864 | 0.9912 | 3.1224 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7483.098 | 1.0067 | 1.0043 | 3.1224 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7483.098 | 0.9968 | 0.9980 | 3.1224 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7483.098 | 0.9916 | 0.9946 | 3.1224 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7483.098 | 0.9202 | 0.9474 | 3.1224 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7483.098 | 0.8838 | 0.9224 | 3.1224 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7483.098 | 0.6359 | 0.7301 | 3.1224 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7483.098 | 0.5996 | 0.6978 | 3.1224 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7483.098 | 0.5399 | 0.6417 | 3.1224 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7484.07 | 1.0125 | 1.0101 | 2.4739 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7484.07 | 0.9854 | 0.9882 | 2.4739 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7484.07 | 1.0015 | 1.0012 | 2.4739 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7484.07 | 1.0699 | 1.0553 | 2.4739 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7484.07 | 1.0003 | 1.0002 | 2.4739 |