Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
---|---|---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7484.07 | 0.8647 | 0.8859 | 2.4739 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7484.07 | 0.7550 | 0.7852 | 2.4739 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7484.07 | 0.0601 | -0.3581 | 2.4739 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7484.07 | 0.0269 | -0.5360 | 2.4739 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7484.09 | 0.9456 | 0.9583 | 2.6525 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7484.09 | 0.9579 | 0.9678 | 2.6525 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7484.09 | 0.8789 | 0.9050 | 2.6525 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7484.09 | 0.9519 | 0.9631 | 2.6525 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7484.09 | 0.8555 | 0.8857 | 2.6525 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7484.09 | 0.6308 | 0.6811 | 2.6525 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7484.09 | 0.5498 | 0.5962 | 2.6525 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7484.09 | 0.6075 | 0.6574 | 2.6525 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 133 | uM | 7484.09 | 0.5130 | 0.5550 | 2.6525 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7484.098 | 1.0338 | 1.0256 | 2.6137 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7484.098 | 0.9426 | 0.9553 | 2.6137 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7484.098 | 0.9741 | 0.9800 | 2.6137 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7484.098 | 1.0045 | 1.0034 | 2.6137 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7484.098 | 0.9592 | 0.9684 | 2.6137 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7484.098 | 0.7798 | 0.8185 | 2.6137 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7484.098 | 0.6710 | 0.7168 | 2.6137 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7484.098 | 0.2282 | 0.1364 | 2.6137 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7484.098 | 0.0203 | -0.5501 | 2.6137 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7485.092 | 1.0135 | 1.0074 | 3.6408 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7485.092 | 0.9937 | 0.9965 | 3.6408 | |
MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7485.092 | 0.9739 | 0.9855 | 3.6408 |