Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10874.15 | 0.9787 | 0.9533 | 0.9133 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10874.15 | 0.9475 | 0.8854 | 0.9133 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10874.15 | 0.8893 | 0.7590 | 0.9133 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10874.15 | 0.9406 | 0.8704 | 0.9133 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10874.15 | 0.7126 | 0.3801 | 0.9133 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10874.15 | 0.3609 | -0.3446 | 0.9133 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10874.15 | 0.1479 | -0.7532 | 0.9133 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12220.16 | 0.9669 | 0.8530 | 0.4410 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12220.16 | 1.0315 | 1.1457 | 0.4410 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12220.16 | 1.0624 | 1.2941 | 0.4410 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12220.16 | 1.0459 | 1.2141 | 0.4410 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12220.16 | 0.9472 | 0.7685 | 0.4410 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12220.16 | 1.0060 | 1.0275 | 0.4410 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12220.16 | 0.7736 | 0.1176 | 0.4410 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12220.16 | 0.4324 | -0.7012 | 0.4410 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12220.16 | 0.2963 | -0.8731 | 0.4410 | ||
| SK-BR-3 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 11851.16 | 0.9924 | 0.9869 | 1.1668 | ||
| SK-BR-3 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 11851.16 | 0.9772 | 0.9608 | 1.1668 | ||
| SK-BR-3 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 11851.16 | 0.9774 | 0.9611 | 1.1668 | ||
| SK-BR-3 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 11851.16 | 0.9669 | 0.9431 | 1.1668 | ||
| SK-BR-3 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 11851.16 | 0.9855 | 0.9751 | 1.1668 | ||
| SK-BR-3 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 11851.16 | 0.9360 | 0.8898 | 1.1668 | ||
| SK-BR-3 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 11851.16 | 0.9479 | 0.9103 | 1.1668 | ||
| SK-BR-3 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 11851.16 | 0.8499 | 0.7398 | 1.1668 | ||
| SK-BR-3 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 11851.16 | 0.6692 | 0.4174 | 1.1668 |